Bronchofibroscopy (BFS) in patients with respiratory failure caused by lung diseases and concomitant cardiovascular diseases involves deterioration of ventilation of the lungs. One of the most effective methods for preventing the complications is respiratory support by high-frequency assisted ventilation of the lungs (HFAVL). Oxygen is commonly used for this purpose, but its use can be limited by physiological and technological reasons. We compared HFAVL with oxygen and air during BFS in 97 cancer patients with restrictive and obstructive ventilation disorders and (in 70%) concomitant cardiovascular diseases. Monitoring of cardiorespiratory parameters and analysis of gaseous composition of the blood during BFS showed that like oxygen, air HFAVL prevented the deterioration of alveolar ventilation. On the other hand, blood oxygenation was not notably improved during air HFAVL in patients with pronounced hypoxemia, though subjectively BFS was better tolerated. Use of air extends the potentialities of HFAVL in the treatment of patients with respiratory failure in cases when oxygen in unavailable.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Physiological effects of combined breathing and physical training in middle-aged and older adults.
J Phys Ther Sci
January 2025
Center for Frontier Medical Engineering, Chiba University, Japan.
[Purpose] The safety and physiological effects of combined training with breathing resistance and sustained physical exertion in middle-aged and older adults remain unclear. This pilot study investigated the safety and physiological benefits of this training method in older adults. [Participants and Methods] Participants aged 55-75 without respiratory, circulatory, or metabolic diseases were randomly divided into two groups: a combined breathing and physical training group and a control group.
View Article and Find Full Text PDFEffects of ultrasound-guided stellate ganglion block on intrapulmonary shunt and oxygenation in patients with single-lung ventilation.
Front Surg
December 2024
Department of Anesthesiology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, Fujian, China.
Background: Single-lung ventilation (SLV) is a widely used procedure in thoracic surgery; however, it can lead to hypoxemia, which is attributed to intrapulmonary shunt and hypoxic pulmonary vasoconstriction. Stellate ganglion blockade (SGB) has shown protective effects during SLV in various pulmonary conditions. The objective of the study was to assess the clinical utility of ultrasound-guided SGB in patients undergoing thoracoscopic pulmonary lobectomy through a prospective clinical trial.
View Article and Find Full Text PDFArtificial intelligence in respiratory care.
Front Digit Health
December 2024
Faculty of Engineering and Computing, Liwa College, Abu Dhabi, United Arab Emirates.
The evolution of artificial intelligence (AI) has revolutionised numerous aspects of our daily lives, with profound implications across various sectors, including healthcare. Although the concept of AI in healthcare was introduced in the early 1970s, the integration of this technology in healthcare is still in the evolution phase. Despite barriers, the current decade is witnessing an increased utility of AI into diverse specialities of the medical field to enhance precision medicine, predict diagnosis, therapeutic results, and prognosis; this includes respiratory medicine, critical care, and in their allied specialties.
View Article and Find Full Text PDFTreatment of pneumothorax and bronchopleural fistula by extracorporeal membrane oxygenation in a neonate: a case report.
Front Pediatr
December 2024
Department of Pediatric Intensive Care Unit, Gansu Provincial Maternity and Child Care Hospital, Lanzhou, Gansu, China.
Intractable pneumothorax secondary to bronchopulmonary fistula is a rare complication in neonates. We present the first report of a newborn with spontaneous pneumothorax and bronchopleural fistula treated with extracorporeal membrane oxygenation (ECMO). Positive pressure mechanical ventilation resulted in persistent air leakage from the bronchopleural fistula.
View Article and Find Full Text PDFDetection of aberrant locomotor activity in a mouse model of lung cancer via home cage monitoring.
Front Oncol
December 2024
Department of Experimental Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Introduction: Lung cancer is the first cause of cancer death in the world, due to a delayed diagnosis and the absence of efficacy therapies. KRAS mutation occurs in 25% of all lung cancers and the concomitant mutations in LKB1 determine aggressive subtypes of these tumors. The improvement of therapeutical options for KRASG12C mutations has increased the possibility of treating these tumors, but resistance to these therapies has emerged.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!