Impact of graft material configuration on stent-graft endoleak in vitro.

J Vasc Interv Radiol

Department of Radiology, Beth Israel Deaconess Medical Center-West Campus, 330 Brookline Avenue, Boston, Massachusetts 02215, USA.

Published: December 2001

Purpose: To assess the effect of different attachment patterns between graft materials and stents on type I endoleak.

Materials And Methods: Nitinol stents were covered with a coating of Tegaderm in either a straight-edged pattern across the stent cells or a contoured zigzag pattern conforming to the stent skeleton's honeycomb-shaped cells. The stent-grafts were deployed in an ex vivo circuit across a gap of tubing to simulate an aneurysm cavity. Fluid leaking from the gap for more than 30 minutes was recorded as endoleak. Two contoured attachment patterns (short and long necks) and four straight-edged patterns with necks of varying length were tested. Each experiment was repeated 15 times.

Results: The length of the aneurysm neck covered by the graft material was inversely related to the rate of endoleak. The zigzag pattern of graft attachment demonstrated significantly less endoleak than the straight-edged pattern in the setting of a short aneurysm neck (0.25 mL vs 47.3 mL).

Conclusion: Adopting the contoured (zigzag) attachment of graft material to stents minimizes endoleak in vitro, particularly in the setting of a short aneurysm neck.

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1051-0443(07)61702-3DOI Listing

Publication Analysis

Top Keywords

graft material
12
aneurysm neck
12
endoleak vitro
8
attachment patterns
8
straight-edged pattern
8
contoured zigzag
8
zigzag pattern
8
setting short
8
short aneurysm
8
endoleak
5

Similar Publications

Dual-sided centripetal microgrooved poly (D,L-lactide-co-caprolactone) disk encased in immune-regulating hydrogels for enhanced bone regeneration.

Mater Today Bio

February 2025

China Uruguay Bio-Nano Pharmaceutical Joint Laboratory, Institute of Neuroregeneration and Neurorehabilitation, Qingdao University, 308 Ningxia Road, Qingdao, 266071, Shandong, China.

Well-designed artificial scaffolds are urgently needed due to the limited self-repair capacity of bone, which hampers effective regeneration in critical defects. Optimal scaffolds must provide physical guidance to recruit cells and immune regulation to improve the regenerative microenvironment. This study presents a novel scaffold composed of dual-sided centripetal microgrooved poly(D,L-lactide-co-caprolactone) (PLCL) film combined with a dynamic hydrogel containing prednisolone (PLS)-loaded Prussian blue nanoparticles (PB@PLS).

View Article and Find Full Text PDF

Interfacial solar vapor generation (ISVG) accompanied by photocatalytic degradation holds immense potential to mitigate water scarcity and pollution. Distinct from the two detached functional components (photothermal agent and photocatalyst) in a conventional evaporator, in this study, an all-in-one photothermal/catalytic agent, nitrogen-containing honeycomb carbon nanosheets (NHC), was engineered for synergistic high-efficiency steam generation and photocatalysis functions. It was demonstrated that the superoxide radical generated on the surface of NHC conferred its catalytic activity to the photodegradation of organic pollutants under full solar spectrum irradiation.

View Article and Find Full Text PDF

Objective: A series of webinars covering widespread knowledge on paediatric cardiology and cardiac surgery topics was initiated by Association for European Paediatric and Congenital Cardiology, serving towards preparation for the Association for European Paediatric and Congenital Cardiology certification in paediatric and congenital cardiology. This study investigated the impact of webinars as educational tools for junior paediatric cardiologists in the post-COVID-19 pandemic era.

Materials And Methods: A cross-sectional survey design study using an online survey as a tool for the assessment of trainees.

View Article and Find Full Text PDF

Dynamic Brush Surface Inducing Mobile Crystallization for Sustainable Spray Cooling Using Saline.

Nano Lett

January 2025

School of Nanoscience and Materials Engineering, Henan University, Zhengzhou, Henan 450046, China.

Spray cooling, which dissipates heat through droplet evaporation, is an efficient cooling method. Using seawater instead of freshwater in spraying is appealing given the intensifying global water crisis. However, seawater-based cooling suffers from salt accumulation on hot surfaces.

View Article and Find Full Text PDF

PBAE-PEG based lipid nanoparticles for lung cell-specific gene delivery.

Mol Ther

January 2025

Perinatal Institute, Division of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA. Electronic address:

Exemplified by successful use in COVID-19 vaccination, delivery of modified mRNA encapsulated in lipid nanoparticles provides a framework for treating various genetic and acquired disorders. However, lipid nanoparticles that can deliver mRNA into specific lung cell types have not yet been established. Here, we sought whether poly(®-amino ester)s (PBAE) or PEGylated PBAE (PBAE-PEG) in combination with 4A3-SC8/DOPE/cholesterol/DOTAP lipid nanoparticles (LNP) could deliver mRNA into different types of lung cells in vivo.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!