LH, FSH, estradiol-17beta, progesterone, 20alpha-dihydroprogesterone, 17alpha-hydroxyprogesterone, delta4-androstenedione and testosterone are determined by radioimmunoassay in serum daily during 11 menstrual cycles. Three of them had to be considered as cycles with corpus luteum insufficiency on the basis of basal body temperature, length of the luteal phase and the pattern of progesterone concentration in serum. One woman conceived during the investigated cycle. The present concepts of the regulation of ovulation are discussed on the basis of the chronological relationshp of changing endocrine parameters in serum during the cycles. The analysis of the hormone concentrations in serum during the cycles with corpus luteum insufficiency supports the view that corpus luteum insufficiency could be caused by an insufficient stimulation of the growing follicle, but other ethiological factors have also to be considered.
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http://dx.doi.org/10.1007/BF00672283 | DOI Listing |
Reprod Sci
January 2025
Physiology Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran.
Polycystic ovary syndrome (PCOS) is a common cause of infertility in women, characterized by metabolic and hormonal irregularities. We investigated the effects of placenta-derived mesenchymal stem cells (PDMSCs) and platelet-rich plasma (PRP), as well as their combination on follicular development, hormonal profile, inflammatory parameters, and insulin resistance in a model of PCOS. In this study, 25 female Wistar rats were randomly allocated into five groups: Sham (given a dose of 1 mL of a 0.
View Article and Find Full Text PDFPhytother Res
January 2025
Constantine the Philosopher University in Nitra, Nitra, Slovak Republic.
This narrative review describes the provenance and chemical composition of Vitex agnus-castus, as well as the currently available knowledge concerning its action. To search the related articles, Cochrane Library, PubMed, Web of Science, SCOPUS databases between the years 1995 and 2024, and the keywords "Vitex," "review," "fertility," "ovarian" and "mechanisms" were used in various combinations. The data listed in this review demonstrate that Vitex agnus-castus and its constituents (isoflavones and essential oils) affect a number of physiological actions via multiple extra- and intracellular mechanisms of action.
View Article and Find Full Text PDFVet Sci
January 2025
School of Veterinary Medicine, Ceará State University (UECE), Fortaleza 60714-903, CE, Brazil.
We investigated whether microalgae or linseed supply during the early postpartum period affects ovarian restimulation and supports the first postpartum ovulation in lactating anovulatory goats. Thirty-eight An-glo-Nubian-crossbred adult goats were allocated into three groups, one with a control diet ( = 12), fed a total mixed ration (TMR) comprising chopped elephant grass and concentrate; an algal diet ( = 13), fed TMR + green microalgae (1% dry matter); and a linseed diet ( = 13), TMR + linseed (12% dry matter). Supplements were furnished from the second to fifth week (time of weaning).
View Article and Find Full Text PDFFront Mol Biosci
January 2025
Department of Animal Anatomy and Physiology, Faculty of Biology and Biotechnology, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Introduction: Chronic inflammation caused by infections has a significant negative impact on the reproductive system and impairs fertility. The corpus luteum (CL) plays a central role not only in regulating the ovary cycle, but also in implantation of the embryo and maintenance of early pregnancy through the secretion of progesterone. Understanding the intricate interplay between inflammatory processes and reproductive organ's function is crucial for the development of effective therapeutic strategies to alleviate reproductive disorders and improve fertility.
View Article and Find Full Text PDFCureus
December 2024
Hematology, Dubai Hospital, Dubai Health, Dubai, ARE.
Bernard-Soulier syndrome (BSS) is a rare qualitative condition of platelets wherein deficiency of platelet surface glycoproteins (GP) Ib, IX, and V forms the Ib-IX-V complex, leading to impaired hemostasis. Although it commonly presents as prolonged bleeding in general, women in the reproductive phase report additional complications during menstruation, pregnancy, and childbirth. In women of reproductive age, menorrhagia is a frequent complaint.
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