Objective: The potential therapeutic effects of repetative transcranial magnetic stimulation (rTMS) are being examined in various neuropsychiatric illnesses. This study assesses the cognitive performance of depressed patients receiving high or low frequency rTMS for 10 days.
Methods: 18 depressed patients participated in a randomized double-blind cross-over study exploring the antidepressant effects of 2 weeks (10 daily) of sham, 1 Hz, or 20 Hz rTMS administered over the left dorsolateral prefrontal cortex at 100% of motor threshold (MT). A subgroup completed a battery of cognitive tests at baseline and following each 2-week phase of treatment, and differences in performance were assessed using paired t -tests and were correlated with the degree of clinical improvement using Hamilton Depression Rating Scale scores.
Results: There were no major changes in cognitive test scores as a result of 10 days of either 1 Hz or 20 Hz rTMS. Moreover, any minor attenuations in cognition were not related to the degree of clinical improvement.
Conclusions: Cognitive functioning in many domains following 2 weeks of 1 Hz or 20 Hz rTMS at 100% MT over the left dorsolateral prefrontal cortex in depressed patients is not disrupted.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/00124509-200112000-00005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Studies across multiple addictions have suggested that repetitive transcranial magnetic stimulation (rTMS) applied to the left dorsolateral prefrontal cortex (L-DLPFC) reduces cue-induced-craving (CIC), however there are no studies in treatment seeking participants with cannabis use disorder (CUD). In this secondary analysis of a previously completed trial, we explore whether a multi-session course of rTMS reduces CIC in CUD.
Methods: Seventy-one participants with ≥moderate CUD (age=30.
Cortical hypometabolism as a predictor of intermittent theta burst stimulation response in treatment-resistant depression patients: An open-label study.
Indian J Psychiatry
December 2024
Department of Nuclear Medicine, AIIMS, Bilaspur, Himachal Pradesh, India.
Background: Intermittent theta burst stimulation (iTBS) is an accepted and approved brain stimulation technique to treat patients with treatment-resistant depression.
Aim: Using neuroimaging, this open-label study aimed to predict the response by observing glucose metabolism with the help of 18-FDG PET scan.
Methods: A total of 25 treatment-resistant depression patients received 15 sessions of iTBS on the left dorsolateral prefrontal cortex.
Neuroenhancement by repetitive transcranial magnetic stimulation (rTMS) on DLPFC in healthy adults.
Cogn Neurodyn
December 2025
CIPCE, School of Electrical and Computer Engineering, College of Engineering, University of Tehran, North Kargar Ave., Tehran, Iran.
The term "neuroenhancement" describes the enhancement of cognitive function associated with deficiencies resulting from a specific condition. Nevertheless, there is currently no agreed-upon definition for the term "neuroenhancement", and its meaning can change based on the specific research being discussed. As humans, our continual pursuit of expanding our capabilities, encompassing both cognitive and motor skills, has led us to explore various tools.
View Article and Find Full Text PDFMonitoring nap deprivation-induced fatigue using fNIRS and deep learning.
Cogn Neurodyn
December 2025
Faculty of Psychology, Naval Medical University (Second Military Medical University), No. 800 Xiangyin Road, Yangpu District, Shanghai, 200433 China.
Fatigue-induced incidents in transportation, aerospace, military, and other areas have been on the rise, posing a threat to human life and safety. The determination of fatigue states holds significant importance, especially through reliable and conveniently available physiological indicators. Here, a portable custom-built fNIRS system was used to monitor the fatigue state caused by nap deprivation.
View Article and Find Full Text PDFApplication of virtual reality technology improves the functionality of brain networks in individuals experiencing pain.
World J Clin Cases
January 2025
Department of Psychiatric Internal Medicine, Sunlight Brain Research Center, Hofu 7470066, Yamaguchi, Japan.
Medical procedures are inherently invasive and carry the risk of inducing pain to the mind and body. Recently, efforts have been made to alleviate the discomfort associated with invasive medical procedures through the use of virtual reality (VR) technology. VR has been demonstrated to be an effective treatment for pain associated with medical procedures, as well as for chronic pain conditions for which no effective treatment has been established.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!