Investigation of blood flow microcirculation by diffusing wave spectroscopy.

This article presents a technique and a setup for noninvasive in vivo studies of cutaneous microcirculation. The technique is based on the analysis of intensity fluctuations of scattered coherent light. The analysis is made in terms of diffusing wave spectroscopy. The developed technique can be used in clinical practice to determine the motion pattern of scattering particles (such as red blood cells) in randomly inhomogeneous media (such as biological tissues). The average size of scattering particles can be comparable to the wavelength of scattered radiation.