Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1203/00006450-200112000-00006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Effect of low-intensity laser-therapy in the correction of encephalopathy in obstructive jaundice].
Vopr Kurortol Fizioter Lech Fiz Kult
December 2024
Polyclinic No. 3 of the Medical Sanitary Unit of the Ministry of Internal Affairs of the Russian Federation, Moscow, Russia.
Unlabelled: Hepatic encephalopathy is an early and severe complication of obstructive jaundice and is characterized by occurrence of non-focal and focal neurological manifestations. Different methods of therapy are applied for disorder correction. Low-intensity laser blood irradiation has a pronounced antioxidant and vasoactive effect.
View Article and Find Full Text PDFTrends of extreme hyperbilirubinemia related infant mortality in select European countries (1990-2019).
Pediatr Res
November 2024
Division of Pediatrics and Neonatal Critical Care, "A. Béclère" Medical Center, Paris; Saclay University Hospital, APHP-Paris, Paris, France.
Article Synopsis
- The study investigates trends in infant mortality rates linked to extreme neonatal hyperbilirubinemia (EHB) in six European countries from 1990 to 2019, revealing a significant decline in such mortality rates over the years.
- Results showed a decrease in EHB-related infant mortality from 21.4 to 4.2 per million live births, with Germany showing the best improvement and Portugal the most significant decline rate.
- The findings underscore the need for national surveillance and tailored guidelines to prevent bilirubin-induced neurological damage, highlighting substantial differences in mortality trends among the countries studied.
Total cholesterol and bilirubin levels are associated with neurologic outcomes in patients with out-of-hospital cardiac arrest.
Intern Emerg Med
November 2024
Department of Emergency Medicine, College of Medicine, Hanyang University, 222-1 Wangsimni-ro, Seongdong-gu, Seoul, 04763, Republic of Korea.
Background: Assessing the neurologic outcomes of patients who experience out of hospital cardiac arrest (OHCA) is challenging. Neurologic outcomes were evaluated using initial nutrition related biochemical markers.
Methods: We used data from a multicentre retrospective observational study, the Korean Cardiac Arrest Resuscitation Consortium (KoCARC) registry.
Homozygous variants in WDR83OS lead to a neurodevelopmental disorder with hypercholanemia.
Am J Hum Genet
November 2024
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Section of Neurology and Developmental Neuroscience, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA; Texas Children's Hospital, Houston, TX 77030, USA. Electronic address:
Article Synopsis
- - WDR83OS encodes a protein called Asterix, which works with another protein, CCDC47, to help fold large proteins correctly, specifically those with transmembrane domains.
- - Recent findings linked mutations in CCDC47 and WDR83OS to trichohepatoneurodevelopmental syndrome, showing consistent symptoms like neurodevelopmental disorders, facial dysmorphism, and liver dysfunction across multiple families.
- - A zebrafish model lacking Wdr83os function demonstrated its crucial role in the nervous system and lipid absorption, further establishing a connection between WDR83OS mutations and neurological diseases characterized by elevated bile acids.
Article Synopsis
- Filtered-sunlight phototherapy (FSPT) is shown to be a safe and effective alternative to intensive electric phototherapy (IEPT) for treating neonatal hyperbilirubinemia, with no significant differences in efficacy or safety.
- In a trial with 192 newborns, both treatments showed similar rates of exchange transfusions and mortality, indicating FSPT's non-inferiority.
- Overall, FSPT could be a practical option when electric therapy is unavailable, as it successfully prevented complications and was well-tolerated among treated infants.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!