Heat stroke occurs in the desert area of Saudi Arabia quite frequently and manifest in different patterns including coagulopathy. Frequently encountered complications include renal or hepatic failure, rhabdomyolysis, acute respiratory distress syndrome (ARDS), disseminated intravascular coagulation (DIC), and seizure. Not all of these complications usually occur in the same patient, in case it occurs the mortality reported is significantly high. We describe a case of heat stroke that had nearly all the known complications of heat stroke but recovered from all, except minor neurological deficit in the form of dysarthria and exaggerated deep reflexes.
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[Biological essence of blood stasis-heat syndrome in ischemic stroke and current research status of traditional Chinese medicine prevention and treatment based on thromboinflammation reaction].
Zhongguo Zhong Yao Za Zhi
December 2024
Institute of Basic Theory on Integrated Traditional Chinese and Western Medicine, College of Integrated Traditional Chinese Medicine and Western Medicine, Hunan University of Chinese Medicine Changsha 410208, China.
Blood stasis-heat syndrome is one of the common syndromes of ischemic stroke, which is manifested as syndromes of blood stasis and heat during the pathological progression of patients with ischemic stroke, but there is a lack of systematic research on its biological essence. Thromboinflammation reaction is a newly proposed pathological mechanism highly associated with thrombosis and inflammatory reaction, and it refers to the fact that under the mediation of von Willebrand factor(vWF) and the kallikrein-kinin system, thrombosis and inflammatory reaction interact with each other. Activation of T cells and neutrophils further aggravates thrombosis and worsens the pathological progression of ischemic stroke.
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Department of Nursing, General Hospital of Southern Theatre Command of PLA, Guangzhou, Guangdong, China.
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