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PLoS One
January 2025
Bio Bureau Biotechnology, Rio de Janeiro, Rio de Janeiro, Brazil.
Monitoring biodiversity on a large scale, such as in hydropower reservoirs, poses scientific challenges. Conventional methods such as passive fishing gear are prone to various biases, while the utilization of environmental DNA (eDNA) metabarcoding has been restricted. Most eDNA studies have primarily focused on replicating results from traditional methods, which themselves have limitations regarding representativeness and bias.
View Article and Find Full Text PDFVet Sci
December 2024
College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
Cadmium accumulation in the body can damage a variety of organs and impair their development and functions. In the present study, we investigated the effect of cadmium on the stemness and proliferation of normal bovine mammary epithelial cells (BMECs). Normal bovine mammary epithelial cells treated with cadmium chloride were assessed for the expression of stemness-related proteins and cell proliferation.
View Article and Find Full Text PDFMar Drugs
December 2024
CESAM-Centre for Environmental and Marine Studies, Department of Environment and Planning, Campus Universitário de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
This review is focused on the research, innovation and technological breakthroughs on marine invertebrate collagens and their applications. The findings reveal that research dates back to the 1970s, and after a period of reduced activity, interest in collagens from several marine invertebrate groups was renewed around 2008, likely driven by the increased commercial interest in these biomolecules of marine origin. Research and development are predominantly reported from China and Japan, highlighting significant research interest in cnidarians (jellyfish), echinoderms (sea cucumbers, sea urchins and starfish), molluscs (squid and cuttlefish) and sponges.
View Article and Find Full Text PDFCells
January 2025
CHU Sainte-Justine Research Center, Université de Montréal, Montreal, QC H3T 1C5, Canada.
Stem cells are undifferentiated or partially differentiated cells with an extraordinary ability to self-renew and differentiate into various cell types during growth and development. The epithelial-mesenchymal transition (EMT), a critical developmental process, enhances stem cell-like properties in cells, and is associated with both normal stem cell function and the formation of cancer stem cells. Cell stemness and the EMT often coexist and are interconnected in various contexts.
View Article and Find Full Text PDFCurr Med Chem
January 2025
School of Medicine and Pharmacy, Duy Tan University, Da NangVietnam, Institute of Research and Development, Duy Tan University, Da Nang Vietnam.
Alzheimer's disease (AD) remains a significant challenge in neurology, marked by progressive cognitive decline and neurodegeneration. Despite extensive research efforts, effective treatments are still lacking. Traditional drug discovery is often slow and costly, frequently resulting in limited success.
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