Background: Cervical Intraepithelial Neoplasia (CIN) is a dysplastic lesion that precedes cervical cancer. The diagnosis is made by colposcopic, cytologic and bioptic exams. Therapy may be physical, pharmacological or surgical.
Methods: We prepared a model of interview (consisting of 9 questions) for 33 colposcopic centers in the Lazio region. Our aim was to evaluate their therapeutic strategies for CIN and cervical condylomata. We referred to SIGO 1999 guidelines for CIN therapy and to European guidelines for cervical condylomata therapy.
Results: The centers used drugs more for HPV infections (57%) than for dysplasia (33%). Drug therapy was used more in the past (66.67%). Actually they prefer treating CIN I with electrocoagulation diathermy (DTC), CIN II with loop electrosurgical excision procedures (LEEP) or Laser, CIN III with cold knife conization or LEEP, cervical condylomata with laser or DTC.
Conclusions: The results show that the centers prefer physical therapy. Therapeutic strategies comply with SIGO 1999 guidelines for therapy of CIN and with European guidelines for cervical condylomata partially.
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Human papillomavirus-associated cancers, precancers, and genital warts in Denmark, 2000-2022 - Current burden of disease and population impact of multi-cohort HPV vaccination.
Prev Med
December 2024
Unit of Virus, Lifestyle and Genes, Danish Cancer Institute, Strandboulevarden 49, 2100 Copenhagen O, Denmark; Department of Clinical Medicine, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen N, Denmark; Department of Gynecology, Copenhagen University Hospital Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen O, Denmark. Electronic address:
Article Synopsis
- The study analyzed cancer trends related to human papillomavirus (HPV) in Denmark from 2000 to 2022, focusing on cervical precancer, genital warts, and overall disease burden post-HPV vaccination.
- Findings revealed a significant decline in age-standardized incidence rates (ASRs) for cervical precancer and genital warts, particularly among women, while HPV-associated cancers have been rising in men and non-cervical sites among women.
- The conclusion emphasized that, even with vaccination efforts leading to decreased cases of certain HPV-related conditions, HPV-associated diseases continue to pose a public health challenge, especially among men.
Disproportionate preponderance of HPV genotypes associated with anogenital warts among HIV-positive MSM.
Front Public Health
October 2024
Department of Dermatology and Venerology, Medical University of Innsbruck, Innsbruck, Austria.
Background: In this study, we characterized the HPV genotype distribution in a population of 489 adults already positive for HPV DNA. The study population was divided into two groups: 244 HIV-positive (HIV+) men who have sex with men (MSM) undergoing routine anal screening for sexually transmitted diseases (STDs) and 245 women undergoing routine cervical cancer screening. Acknowledging the fact that women and MSM represent two independent circles of sexual practices, which are-largely-exclusive of each other, we were interested in determining if particular genotypes of human papillomavirus (HPV) disproportionately predominate in one of these circles compared to the other.
View Article and Find Full Text PDFThe impact of Germany's human papillomavirus immunization program on HPV-related anogenital diseases: a retrospective analysis of claims data from statutory health insurances.
Arch Gynecol Obstet
November 2024
EU Real World Evidence, Xcenda GmbH, Lange Laube 31, 30159, Hanover, Germany.
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- HPV is the most common sexually transmitted infection, and its vaccination has been part of Germany's national immunization program since 2007, but uptake rates are still low.
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[Knowledge about human papillomaviruses among students in Germany-a cross-sectional study with a need for action].
Urologie
January 2025
Universitätsklinik und Poliklinik für Urologie, Universitätsklinikum Halle (Saale), Halle (Saale), Deutschland.
Article Synopsis
- The human papillomavirus (HPV) is a common sexually transmitted virus linked to various diseases, and vaccination is encouraged, but awareness and vaccination rates in Germany are low.
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Attitudes toward an HPV vaccine for condyloma acuminata and willingness to undergo vaccination among STD clinic attendees in China: Focus on STI prevention with HPV vaccine.
BMC Public Health
June 2024
Department of Dermatology, Affiliated Hospital of Nantong University, Nantong, China.
Background: Condyloma acuminata (CA) is a common, and recurrent sexually transmitted disease (STD) that greatly contributes to direct health care costs and has a substantial psychosocial impact. Human papillomavirus (HPV) vaccination (containing L1 protein for HPV types 6 and 11) effectively controls CA.
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