A number of multicentric randomized studies have been able to demonstrate a benefit from surgery in high-grade asymptomatic and symptomatic carotid artery stenosis. The benefits of carotid artery endarterectomy are greater in symptomatic than in asymptomatic patients. This means that, in the case of the latter, the benefits and risks of surgery must be considered with special care. The gold standard of the preoperative diagnostic work-up is selective angiography. Since this examination modality is associated with a complication rate of > 1% in this group of patients, there is an increasing tendency to content oneself with such noninvasive procedures as duplex sonography used in combination with cranial and cervical MRI. The life expectancy of patients undergoing carotid artery end-arterectomy is determined mainly by their concomitant cardiac problems. Constant surveillance and optimal treatment of vascular risk factors is therefore essential in these patients.
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