Membrane transport: ubiquitylation in endosomal sorting.

Curr Biol

Institut Jacques Monod, Universités Paris VI and Paris VII, 2 place Jussieu, 75251 PARIS Cedex 05, France.

Published: November 2001

In yeast, membrane proteins from the biosynthetic and endocytic pathways must be ubiquitylated for sorting to inward-budding vesicles in late endosomes, which give rise to multivesicular bodies. A conserved protein complex containing the yeast Vps23p or its mammalian counterpart Tsg101 may act as the ubiquitin receptor.

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http://dx.doi.org/10.1016/s0960-9822(01)00558-9DOI Listing

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