Self-adaptation is a common method for learning online control parameters in an evolutionary algorithm. In one common implementation, each individual in the population is represented as a pair of vectors (x, sigma), where x is the candidate solution to an optimization problem scored in terms of f(x), and sigma is the so-called strategy parameter vector that influences how offspring will be created from the individual. Experimental evidence suggests that the elements of sigma can sometimes become too small to explore the given response surface adequately. The evolutionary search then stagnates, until the elements of sigma grow sufficiently large as a result of random variation. A potential solution to this deficiency associates multiple strategy parameter vectors with a single individual. A single strategy vector is active at any time and dictates how offspring will be generated. Experiments are conducted on four 10-dimensional benchmark functions where the number of strategy parameter vectors is varied over 1, 2, 3, 4, 5, 10, and 20. The results indicate advantages for using multiple strategy parameter vectors. Furthermore, the relationship between the mean best result after a fixed number of generations and the number of strategy parameter vectors can be determined reliably in each case.
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http://dx.doi.org/10.1016/s0303-2647(01)00167-8 | DOI Listing |
PLoS Comput Biol
January 2025
Department of Anatomy and Cell Biology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka, Japan.
Mathematical modeling has been utilized to explain biological pattern formation, but the selections of models and parameters have been made empirically. In the present study, we propose a data-driven approach to validate the applicability of mathematical models. Specifically, we developed methods to automatically select the appropriate mathematical models based on the patterns of interest and to estimate the model parameters.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Health Informatics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
School closures are a safe and important strategy for preventing infectious diseases in schools. However, the effects of school closures have not been fully demonstrated, and prolonged school closures have a negative impact on students and communities. This study evaluated class-specific school closure strategies to prevent the spread of seasonal influenza and determine the optimal timing and duration.
View Article and Find Full Text PDFPLoS One
January 2025
Liaoning Ocean and Fisheries Science Research Institute, Liaoning Academy of Agricultural Sciences, Dalian, PR China.
Objective: This study aimed to evaluate the positive effects on anti-oxidation, anti-inflammation, and microbial composition optimization of diabetic mice using tussah (Antheraea pernyi) silk fibroin peptides (TSFP), providing the theoretical foundation for making the use of silk resources of A. pernyi and incorporating as a supplement into the hypoglycemic foods.
Method: The animal model of diabetes was established successfully.
J Antimicrob Chemother
January 2025
Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Objectives: This study aimed to predict the impact of different infusion strategies on pharmacokinetic/pharmacodynamic (PK/PD) target attainment and the potential risk for toxicity in an ICU cohort treated with β-lactams.
Method: Using collected patient data from 137 adult ICU patients, and applying population PK models, individual PK parameters were estimated and used to predict concentrations and target attainment following cefotaxime 2 g q8h, piperacillin/tazobactam 4.5 g q6h and meropenem 1 g q8h, applying 15 min short infusions (SI), 3 h extended infusions (EI) and 24 h continuous infusion (CI).
J Acoust Soc Am
January 2025
School of Information and Electronics, Beijing Institute of Technology, Beijing 100081, People's Republic of China.
A complex-valued neural process method, combined with modal depth functions (MDFs) of the ocean waveguide, is proposed to reconstruct the acoustic field. Neural networks are used to describe complex Gaussian processes, modeling the distribution of the acoustic field at different depths. The network parameters are optimized through a meta-learning strategy, preventing overfitting under small sample conditions (sample size equals the number of array elements) and mitigating the slow reconstruction speed of Gaussian processes (GPs), while denoising and interpolating sparsely distributed acoustic field data, generating dense field data for virtual receiver arrays.
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