Levofloxacin is one of the most commonly prescribed antibiotics for both inpatient and outpatient care of respiratory tract infection. It is generally well tolerated, and it has an excellent safety profile. We report a case of severe acute liver toxicity that apparently complicated intravenous administration of levofloxacin, which resolved after discontinuation of the drug.

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http://dx.doi.org/10.1086/338156DOI Listing

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Article Synopsis
  • Diagnosing drug-induced acute pancreatitis is often missed, as it's a rare condition that requires ruling out other common causes like alcohol and gallstones.
  • Levofloxacin, an antibiotic used for bacterial infections, can occasionally lead to acute pancreatitis, despite its more common side effects.
  • A case study highlights a woman who developed acute pancreatitis after taking levofloxacin for a urinary tract infection, with diagnosis confirmed through clinical and laboratory evaluations.
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Drug-induced pancreatitis is a rare entity accounting for less than 2% of acute pancreatitis (AP). Quinolones are commonly used antimicrobials with occasional reports of pancreatitis. We present the case of a 74-year-old man who was diagnosed with acute cystitis five days before hospital admission and was treated with levofloxacin (LVF).

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Medication-induced cutaneous hyperpigmentation has variable clinical presentations and is dependent on the specific drug involved. Most commonly, an attentive patient observes such changes early in the course; when missed by the patient, such changes are usually noted by an observant clinician. Clinical diagnosis can be challenging if the patient is on multiple medications because other causes must be excluded.

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Levofloxacin is a fluoroquinolone antibiotic commonly used to treat a wide range of bacterial infections. It is normally well tolerated with the most common side effect being gastrointestinal distress. Severe side effects including neuropsychiatric symptoms are rare but have been observed even in patients who lack risk factors or are otherwise healthy.

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