A new limonoid was isolated from the bark of Khaya senegalensis and identified as 2,6-dihydroxyfissinolide. The assignments of some signals in the (13)C NMR spectrum of fissinolide have been reversed and the signals of the (1)H NMR spectrum of methyl 3beta-acetoxy-6-hydroxy-1-oxomeliac-14-enoate have been assigned. The limonoids only showed moderate antiprotozoal activities.
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http://dx.doi.org/10.1016/s0031-9422(98)00284-2 | DOI Listing |
ScientificWorldJournal
October 2024
University of Maroua, Faculty of Science, Department of Biological Sciences, P.O. Box 814, Maroua, Cameroon.
This study was conducted in the Mandara Mountains in Cameroon and aimed to assess the effects of human activities on woody vegetation in gallery forests, based on floristic inventories and observations made by the government. Firstly, the inventories were carried out in 150 plots of 1000 m each, installed on the banks of watercourses following the band of plant formations. In each plot, woody species were counted and those showing at least one sign of degradation were noted.
View Article and Find Full Text PDFJ Trop Med
March 2024
Council for Scientific and Industrial Research (CSIR), Water Research Institute, Biomedical and Public Health Research Unit, P.O. Box AH 38, Accra, Ghana.
Background: Schistosomiasis is caused by parasitic flatworms and the disease is endemic to most countries in sub-Saharan Africa including Ghana. The current therapeutic agent for managing this disease solely relies on praziquantel. The continual dependence on this single available drug could lead to possible drug resistance.
View Article and Find Full Text PDFBMC Plant Biol
September 2024
Departamento de Farmácia e Nutrição, Universidade Federal do Espírito Santo, Alegre, Espírito Santo, 29500-000, Brasil.
Background: African mahogany species (Khaya sp.) have been introduced to Brazil gaining increasing economic interest over the last years, as they produce high quality wood for industrial applications. To this date, however, the knowledge available on the genetic basis of African mahogany plantations in Brazil is limited, which has driven this study to examine the extent of genetic diversity and structure of three cultivated species (Khaya grandifoliola, Khaya senegalensis and Khaya ivorensis) and their prospects for forest breeding.
View Article and Find Full Text PDFJ Ethnopharmacol
December 2024
Biochemistry Division, National Veterinary Research Institute, Vom, Plateau State, Nigeria. Electronic address:
Ethnopharmacological Relevance: Pastoralists in Nigeria mix Garcinia kola seed (GK), Khaya senegalensis stem bark (KS), and Vernonia amygdalina leaves (VA) to treat leptospirosis.
Aim: To determine the in vitro and in vivo effect on single and combination therapy on Leptospira interrogans-infected mice.
Materials And Methods: Evaluation of in vitro assay for anti-leptospiral motility of the extracts was carried out in triplicates.
Heliyon
July 2024
Institute of Traditional and Alternative Medicine, University of Health and Allied Sciences, Ho, Ghana.
The traditional free-range system of livestock rearing contributes to the socioeconomic well-being of most rural households in Ghana. The traditional management system exposes livestock to a high disease incidence, but healthcare support for animal production is limited. Ethnoveterinary practice is an integral part of livestock treatment, particularly in rural communities where veterinary services are poor.
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