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Anti-aflatoxin potential of phenolic compounds from common beans (Phaseolus vulgaris L.).
Food Chem
December 2024
Centro para Investigaciones en Granos y Semillas, Universidad de Costa Rica, 11501 San Pedro, San José, Costa Rica. Electronic address:
Common beans (Phaseolus vulgaris L.) are widely consumed legumes in Latin America and Africa, valued for their nutritional compounds and antioxidants. Their high polyphenol content contributes to the antioxidant properties, with bioactive compounds showing antifungal and antimycotoxin effects.
View Article and Find Full Text PDFOchratoxin A and AFM1 in Cheese and Cheese Substitutes: LC-MS/MS Method Validation, Natural Occurrence, and Risk Assessment.
Toxins (Basel)
December 2024
Centre of Excellence in Mycotoxicology and Public Health, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, B-9000 Ghent, Belgium.
Cheese is vulnerable to contamination with mycotoxins, particularly ochratoxin A (OTA) and aflatoxin M1 (AFM1). This study aims to develop and validate an analytical method for the detection and quantification of OTA and AFM1 in cheese and to assess their prevalence and associated risks. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was validated for detecting these mycotoxins in 41 cheese samples, including firm-ripened, spreadable, and plant-based alternatives.
View Article and Find Full Text PDFVariations in Kojic Acid Production and Corn Infection Among Isolates Suggest a Potential Role as a Virulence Factor.
Toxins (Basel)
December 2024
Food and Feed Safety Research Unit, Southern Regional Research Center, US Department of Agriculture, New Orleans, LA 70124, USA.
Kojic acid is a secondary metabolite with strong chelating and antioxidant properties produced by and . Although antioxidants and chelators are important virulence factors for plant pathogens, the ecological role of kojic acid remains unclear. We previously observed a greater gene expression of antioxidants, especially kojic acid, by non-aflatoxigenic when co-cultured with aflatoxigenic Aflatoxin production was also reduced.
View Article and Find Full Text PDFA Multi-Enzyme Complex That Mitigates Hepatotoxicity, Improves Egg Production and Quality, and Enhances Gut and Liver Health in Laying Hens Exposed to Trace Aflatoxin B.
Toxins (Basel)
November 2024
Key Laboratory of Animal Nutrition and Feed Science in East China, Ministry of Agriculture, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
Aflatoxin B is a prevalent secondary hazardous metabolite generated by fungus present in feed ingredients and the surrounding environment: enzymes are currently being recognized as an efficient and promising approach to reducing the associated risks. The objective of this study was to assess the effects of varying doses of enzyme complexes on several parameters in laying hens that were exposed to aflatoxin. During an 8-week experiment, a total of 288 Yukou Jingfen No.
View Article and Find Full Text PDFThe Role of AFB1, OTA, TCNs, and Patulin in Forensic Sciences: Applications in Autopsy, Criminal Investigations, and Public Health Prevention.
Toxins (Basel)
November 2024
Institute of Legal Medicine, Department of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.
Mycotoxins, specifically aflatoxin B1 (AFB1), ochratoxin A (OTA), trichothecenes (TCNs), and patulin, are a group of secondary metabolites that can contaminate food, leading to severe health implications for humans. Their detection and analysis within forensic toxicology are crucial, particularly as they can be implicated in cases of poisoning, foodborne illnesses, or lethal chronic exposure. However, little is known about the application that mycotoxins could have in forensic investigations and especially about the possibility of extracting and quantifying these molecules on tissues or post-mortem fluids collected at autopsy.
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