Objective: To investigate the effect of rehabilitation therapy for short bowel syndrome on patients' nutritional status and intestinal adaptation.
Methods: Twenty seven patients with short bowel syndrome with the average age of 38.5 +/- 19.3 years, the residual small intestine of the length of 15 to 80 cm, ileocecal valve being preserved in 15 cases, and an average time between the onset of short bowel syndrome and rehabilitation therapy of 86 +/- 105 d received 29 courses of rehabilitation therapy including enteral or parenteral nutrition, glutamine, recombinant human growth hormone and rehabilitation diet from January 1997 to July 2000.
Results: After the treatment, the patients' nutritional status improved markedly, their intestinal absorptive capacity improved too. Eight patients were followed up for more than 2 y, 4 of them (50%) had weaned from total parenteral nutrition. Thirteen patients were followed up for more than 1 y, 10 of them (76.9%) had weaned from total parenteral nutrition.
Conclusion: Rehabilitation therapy for short bowel syndrome improves patients' nutritional status effectively and promote intestinal adaptation. Early initiation of rehabilitation therapy promotes intestinal adaptation, and increases patients' liability to wean from total parenteral nutrition.
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