Problem: Air embolisms frequently occur during neurosurgical operations. For detection of air embolisms, a re-usable doppler probe, integrated in a central venous line, is described. In an in-vitro test series the measuring sector as well as the function of a 8 MHz doppler probe are presented.
Method: The 8 MHz doppler probe is a 1.1 mm diameter cable, into the distal end of which a cylindrical doppler crystal from lead-circonate-titanate (PZT5) of 2 x 1.7 mm is integrated and connected with a doppler unit. The detection of micro bubbles with a volume of 0.4-5 microliters was effected in still liquid for simple measuring of the spatial characteristics of the probe as well as in flowing liquid for simulation of a blood circulation system.
Results: The doppler probe detected qualitatively and reproducibly all gas bubbles offered up to 4 cm around the tip of the probe.
Conclusion: A reliable detection of micro-bubbles in this test model is possible by means of a 8 Mhz doppler probe. Further animal and clinical studies are planned.
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http://dx.doi.org/10.1007/s001010100202 | DOI Listing |
Proc Natl Acad Sci U S A
January 2025
Faculty of Technical Chemistry, Institute of Chemical Technologies and Analytics, Technische Universität Wien, Vienna 1060, Austria.
Atomic force microscopy-infrared spectroscopy (AFM-IR) is a photothermal scanning probe technique that combines nanoscale spatial resolution with the chemical analysis capability of mid-infrared spectroscopy. Using this hybrid technique, chemical identification down to the single molecule level has been demonstrated. However, the mechanism at the heart of AFM-IR, the transduction of local photothermal heating to cantilever deflection, is still not fully understood.
View Article and Find Full Text PDFAnn Card Anaesth
January 2025
Department of Cardiothoracic and Vascular Anaesthesia, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Background: This study aimed to assess the accuracy of tricuspid spectral Doppler (E/A) and tissue Doppler parameters (E/E') to diagnose right ventricular diastolic dysfunction (RVDD) in comparison to American Society of Echocardiography (ASE criteria) in pediatric tetralogy of Fallot (TOF) patients after surgical repair.
Methods: This prospective, observational study was done at a tertiary care hospital involving 40 pediatric TOF patients aged less than 2 years who underwent complete intracardiac repair with cardiopulmonary bypass (CPB). Echocardiographic observations were made using a pediatric transesophageal echocardiography probe after surgical repair in the post-CPB period.
Microvasc Res
January 2025
Primary Health Care Center, Department of Health, Medicine and Caring Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden; Wallenberg Centre for Molecular Medicine, Linköping University, Linköping, Sweden. Electronic address:
Introduction: Little is known about the day-to-day variability of different skin microcirculation parameters, and how this variability is influenced by age and sex. The aim was to examine the day-to-day variability of microcirculatory parameters in relation to age and sex.
Methods: The cutaneous microcirculation was measured using a fiber optic probe integrating laser Doppler flowmetry (LDF) and diffuse reflectance spectroscopy (DRS) to measure oxygen saturation, red blood cell (RBC) tissue fraction, speed-resolved and conventional perfusion.
Ultramicroscopy
January 2025
Christian Doppler Laboratory for Sustainable Hard Coatings at the Department of Materials Science, Montanuniversität Leoben, Franz-Josef-Straße 18, 8700 Leoben, Austria.
The impact of the laser wavelength on accuracy in elemental composition analysis in atom probe tomography (APT) was investigated. Three different commercial atom probe systems - LEAP 3000X HR, LEAP 5000 XR, and LEAP 6000 XR - were systematically compared for a TiN model coating studying the effect of shorter laser wavelengths, especially in the deep ultraviolet (DUV) range, on the evaporation behavior. The findings demonstrate that the use of shorter wavelengths enhances the accuracy in elemental composition, while maintaining similar electric field strengths.
View Article and Find Full Text PDFNeurotherapeutics
January 2025
John Hopkins University Applied Physics Laboratory, Laurel, MD, 20723, USA.
Acute brain injury (ABI) is a complex disease process that begins with an initial insult followed by secondary injury resulting from disturbances in cerebral physiology. In the metabolically active brain, early recognition of physiologic derangements is critical in enabling clinicians with the insight to adjust therapeutic interventions and reduce risk of ischemia and permanent injury. Current established approaches for monitoring cerebral physiology include the neurologic physical examination, traditional brain imaging such as computed tomography (CT) and magnetic resonance imaging (MRI), electroencephalography (EEG), and bedside modalities such as invasive parenchymal probes and transcranial doppler ultrasound.
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