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| http://dx.doi.org/10.1136/emj.18.6.419 | DOI Listing |
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The NMDAR-BK channelosomes as regulators of synaptic plasticity.
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Departamento de Ciencias Médicas Básicas, Facultad de Ciencias de la Salud-sección Medicina, Universidad de La Laguna, Tenerife, ES-38071, Spain.
Large conductance voltage- and calcium-activated potassium channels (BK channels) are extensively found throughout the central nervous system and play a crucial role in various neuronal functions. These channels are activated by a combination of cell membrane depolarisation and an increase in intracellular calcium concentration, provided by calcium sources located close to BK. In 2001, Isaacson and Murphy first demonstrated the coupling of BK channels with N-methyl-D-aspartate receptors (NMDAR) in olfactory bulb neurons.
View Article and Find Full Text PDFIncorporating Perineorrhaphy into the LeFort Colpocleisis: A Modified Surgical Approach.
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Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06511, USA.
Introduction And Hypothesis: Perineorrhaphy with levator myorrhaphy is considered a standard part of colpocleisis. Typically, this is done through a separate incision after colpocleisis is completed. We present a video to demonstrate a modified approach to LeFort colpocleisis incorporating perineorrhaphy into the procedure.
View Article and Find Full Text PDFLAPS SA: Measuring Attachment to Dogs and Cats Among South American Countries.
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Department of Public Policy, Management, and Analytics, University of Illinois at Chicago, Chicago, IL, USA.
Human biological and cultural evolution is tied to the relationships established with other animals. Attachment is one of the mechanisms established between dogs/cats and humans and allows the generation of affective bonds and close proximity. Many instruments have been used to study attachment of people to their dogs/cats, such as the Lexington Attachment to Pets Scale (LAPS).
View Article and Find Full Text PDFAn intelligent decision-making system for embryo transfer in reproductive technology: a machine learning-based approach.
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Department of Mathematics and Computer Science, Laboratory of Analysis, Modeling and Simulation, Faculty of Sciences Ben M'sik, Hassan II University of Casablanca, Casablanca, Morocco.
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View Article and Find Full Text PDFInvestigation into the effect of phenylalanine gating on anaerobic haem breakdown using the energy landscape approach.
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Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.
We have recently demonstrated a novel anaerobic NADH-dependent haem breakdown reaction, which is carried out by a range of haemoproteins. The Yersinia enterocolitica protein, HemS, is the focus of further research presented in the current paper. Using conventional experimental methods, bioinformatics, and energy landscape theory (ELT), we provide new insight into the mechanism of the novel breakdown process.
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