The impact factor (IF) is the most accurate system currently available for objectively evaluating the scientific productivity of individual researchers and institutions. It represents the quality level of a periodical and, at the same time, is a convenient reference parameter for the researcher to use in choosing an appropriate journal before submitting his own work for consideration. From this standpoint, we conducted an analysis of periodicals with the highest IF, including those strictly related to infectious diseases and HIV/AIDS, specialty journals, and general medicine reviews. This was done in order to determine just how much of these journals' total 1998 production consisted of articles concerning HIV infection and AIDS. This examination, conducted through a search of the MEDLINE database, predictably revealed greater interest in the HIV/AIDS topic among journals with the highest IF that focus on infectious diseases, though the same interest revealed when examining specialty journals and general medicine periodicals was not negligible.
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J Leukoc Biol
March 2025
Life Sciences Discipline, Burnet Institute, Melbourne, VIC 3004, Australia.
Enhancement of antibody-dependent cellular cytotoxicity (ADCC) is a promising adjunct approach to achieve HIV control in the absence of antiretroviral therapy but requires the development of potent ADCC-eliciting antibodies which can recognise diverse HIV-infected cell types. A panel of broadly neutralising antibodies (bNAbs) targeting HIV envelope were identified which specifically bind both HIV-infected CD4+ T cells and monocyte-derived macrophages (MDM). Afucosylated versions of these bNAbs containing ≈30% less core fucose were generated and elicited a significant increase in ADCC responses from NK cells against HIV-infected T cell and MDM targets.
View Article and Find Full Text PDFAm J Med
March 2025
Division of Infectious Diseases, Weill Cornell Medical College, New York, NY. Electronic address:
Immunizations, malaria chemoprophylaxis, insect repellent use, and prevention and management of travelers' diarrhea are the cornerstones of the pretravel consultation. This report updates one of these topics, vaccine immunizations, for adult international travelers.
View Article and Find Full Text PDFTravel Med Infect Dis
March 2025
Department of Infectious Diseases, Inflammation Center, Helsinki University Hospital and Helsinki University, Helsinki, 00029 HUS, Finland; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, PO box 3 University of Helsinki (Fabianinkatu 33), 00014, Helsinki, Finland. Electronic address:
Background: The intestinal parasite Dientamoeba fragilis (DF) is spread worldwide and can cause prolonged gastrointestinal symptoms, yet its link to international travel has been scarcely studied. To explore this connection, we examined the association between DF cases and international travel history by destination, comparing the findings to data on Giardia duodenalis (GD), a common travel-acquired intestinal parasite.
Methods: We analysed clinical data from patients with DF or GD infection in the Helsinki Metropolitan Area, categorizing the patients as travellers and non-travellers on the basis of their travel history.
Respir Med
March 2025
Department of Tuberculosis, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing 211132, China. Electronic address:
Introduction: Pleurisy tuberculoma (PTM) is a neoplastic lesion that primarily affects the pleural wall or internal organs. The majority of PTM cases are observed during the treatment of tuberculous pleural effusion(TPE), and although the precise pathogenesis remains unclear, there is a significant association between these two conditions. To identify high-risk factors for the development of PTM, we developed a clinical predictive model aimed at providing more insightful information for the development of PTM.
View Article and Find Full Text PDFInt J Infect Dis
March 2025
Translational Research Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani"- Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy. Electronic address:
Tuberculosis (TB) remains the leading cause of death worldwide from a single infectious disease. An estimated quarter of the world's population, about 2 billion people, has an immune response to Mtb without clinical, microbiological, or radiological signs of TB disease. This condition is known as TB infection (TBI) and carries a lifelong risk of reactivation with 5-10% of individuals eventually developing TB disease during their lifetime.
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