20 patients with peptic ulcer disease of duodenum were studied. We found that metabolic activity of neutrophils in peripheral blood and in mucosa is the same in patients with complicated peptic ulcer. The absorption activity of tissue neutrophils is higher than in blood. During operation we observed an increase of neutrophils' activity both in blood and mucosa. On the 6th day after operation the response of neutrophils recovered. In patients who undergo conservative treatment for peptic ulcer of duodenum the activity of neutrophils decreased significantly. This emphasizes that immunocorrection treatment is indicated to all patients that receive conservative treatment for peptic ulcer.
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