Influence of operative intervention of various kinds on state of cellular and humoral immunity was studied in 49 patients with perforative gastroduodenal ulcer. The immunity indexes in patients constitute the prognostic test for estimation of the disease course severity and postoperative therapy efficacy. Significant lowering of postoperative complications frequency was promoted by application of preparations, stimulating the immune system (metrogyl, tactivin, gamma-globulins) in patients after the operation.

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