Chromatographic separation of the extract of the aerial parts of Dodonaea viscosa L. (family Sapindaceae) afforded beta-sitosterol, stigmasterol, the flavone acacetin-7-methyl ether, the flavonol-3-methyl ethers 4',5,7-trihydroxy-3,6-dimethoxyflavone and penduletin, as well as a new clerodane diterpenoid which was identified by spectral means as 15,16-epoxy-5,9-diepicleroda-3,13(16),14-trien-20,19-olide.
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Small Methods
January 2025
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China.
Nat Prod Res
December 2024
School of Life Sciences, Pharmacy and Chemistry, Kingston University, Kingston, UK.
Phytochemical analysis of the twigs and leaves of , endemic to Kenya, yielded known compounds 3-(3',4'-dimethoxyphenyl)-prop-1-ene (, 3-(3',4'-dimethoxyphenyl)-propenal (), lupeol () and -trachyloban-19-oic acid (), and a tentatively new -clerodane diterpenoid, crotokinondoenolide (). -Trachy-loban-19-oic acid () showed good activity against a panel of drug-resistant strains of and spp with MIC -values of 25 g/mL.
View Article and Find Full Text PDFChin J Nat Med
November 2024
Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan Characteristic Plant Extraction Laboratory, Yunnan Key Laboratory of Research and Development for Natural Products, State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, School of Pharmacy and School of Chemical Science and Technology, Yunnan University, Kunming 650500, China; Southwest United Graduate School, Kunming 650592, China. Electronic address:
Two new nor-ent-halimane diterpenes and three previously unreported nor-clerodane diterpenes, designated callicaintides A-E (1-5), were isolated from Callicarpa integerrima. Compounds 1 and 2 feature a distinctive 5/6-membered ring system, while compounds 3-5 are characterized by progressively truncated carbon skeletons, containing 18, 17, and 16 carbons, respectively. In addition, four known compounds 6-9 were also identified.
View Article and Find Full Text PDFFront Pharmacol
October 2024
Laboratorio de Etnofarmacología, Facultad de Ciencias, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, Mexico.
Heliyon
October 2024
Institute of Chemistry, São Paulo State University, UNESP, Francisco Degni 55, 14800-900, Araraquara, SP, Brazil.
Sw. (Salicaceae) is noted for its morphological and chemical plasticity and pharmacological properties. The present study investigates two of its varieties: var.
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