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Les Cartes Porcelaine of the Mid 19th Century.
J Hist Dent
January 2025
Clinic Director, Cavity Busters Doylestown, Doylestown, PA Adjunct Professor Pediatric Dentistry University of Texas HSC at San Antonio Clinical Professor, Pediatric Dentistry Case Western Reserve School of Dental Medicine.
A unique type of advertising trade card was popular in Europe, mostly Belgium, between 1840 and 1865. These cards were produced with a coating of a white lead substance that gave them a lustrous appearance and feel, resembling porcelain. As attractive as these cards were, producing them oftentimes resulted in lead poisoning for the printers, so few were produced after 1865.
View Article and Find Full Text PDFDeveloping Topics.
Alzheimers Dement
December 2024
Johnson and Johnson Innovative Medicine, San Diego, CA, USA.
Background: Over the last two decades the Alzheimer's biomarker field has progressed dramatically, beginning with the identification of specific analytes in CSF that track with autopsy-confirmed AD, progressing to development of specific PET tracers and CSF assays to monitor brain amyloid and tau burden up to 20 years before symptoms, and now delivery of highly accurate, sensitive, and precise assays for measuring specific Abeta and pTau species in plasma.
Method: Here we present on the development, validation, and clinical utility of Janssen's plasma p217+tau Simoa assay. The assay was initially created for CSF in 2017 and used as a pharmacodynamic marker in the Ph1 posdinemab trials, demonstrating substantial dose dependent reduction in CSF p217+tau.
Charting the path to the implementation of universal health coverage policy in Nigeria through the lens of Delphi methodology.
BMC Health Serv Res
January 2025
Society for Family Health, Abuja, Nigeria.
Background: Expanding access to equitable health insurance is an important lever towards the overall strategy for achieving universal health coverage. In Nigeria, health insurance coverage is low with a renewed government action on increasing access to and coverage of high-quality healthcare services to citizens, particularly for the vulnerable and poor population. Therefore, our study co-creates the priorities for expanding health insurance in Nigeria, focusing on key policy reforms, public advocacy, and innovative financing strategies to ensure broader and more equitable coverage for the population.
View Article and Find Full Text PDFAn Outline on benzimidazole Containing Marketed Drugs with Proton Pump Inhibitor and H Receptor Antagonist Activities.
Mini Rev Med Chem
January 2025
Department of Chemistry, Kurukshetra University, Kurukshetra, Kurukshetra, 136119, India.
Heterocyclic compounds are increasingly used in medicinal chemistry because they are the main components of many biological processes and materials. Benzimidazole remains the core center of the heterocyclic chemical group, with essential traits such as six-five-member connected rings and two nitrogen atoms at the 1,3 position in a six-membered benzene and five-membered imidazole- fused ring system. Molecules with benzimidazole derivatives serve important functions as therapeutic agents and have shown excellent results in clinical and biological research.
View Article and Find Full Text PDFIllusion, dilution, or loss: psychological ownership and GenAI.
Trends Cogn Sci
January 2025
Department of Marketing, ESCP Business School, Heubnerweg 8-10, 14093 Berlin, Germany. Electronic address:
Generative artificial intelligence (GenAI) reshapes and challenges psychological ownership of created content. This article examines how GenAI disrupts original content creators' and GenAI users' sense of ownership and control and illustrates how both can perceive the illusion, dilution, and potential loss of control and ownership of content in the GenAI era.
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