An essential component of prosthetic training in amputees is to achieve full weight bearing through the prosthesis. The end-bearing nature of the intact femur in an individual with a knee disarticulation amputation (KDA) offered a rare opportunity to examine this component. The purpose of this case study was to describe the weight-bearing development in a temporary prosthesis. Longitudinal measurement of gait and balance parameters offer objective data to assess this component of amputee rehabilitation. It was concluded that (1) the temporary prosthesis for a KDA was a successful treatment option in the rehabilitation of a KDA; (2) full weight bearing was achieved in four weeks; and (3) the longitudinal objective measures identified unexpected results.
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http://dx.doi.org/10.1016/s0004-9514(14)60360-3 | DOI Listing |
Life Sci Space Res (Amst)
February 2025
Department of Radiation Oncology, Wake Forest University School of Medicine. Winston-Salem, NC, USA. Electronic address:
Reduced weight-bearing during spaceflight has been associated with musculoskeletal degradation that risks astronaut health and performance in transit and upon reaching deep space destinations. Previous rodent experiments aboard the international space station (ISS) have identified that the spaceflight-induced molecular arthritic phenotype was characterized with an increase in oxidative stress. This study evaluated if treatment with a superoxide dismutase (SOD) mimetic on orbit could prevent spaceflight-induced damage to the knee and hip articular cartilage, and the menisci in rodents.
View Article and Find Full Text PDFFish Shellfish Immunol
January 2025
Key Laboratory of Aquatic Nutrition and Feed Science of Jiangsu Province, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, Jiangsu Province, People's Republic of China. Electronic address:
The Chinese mitten crab (Eriocheir sinensis) is an important component in Chinese aquaculture. Due to its lacking adaptive immune system as a crustacean, it exhibits poor tolerance to environmental stresses, particularly the deleterious impact of lipopolysaccharide (LPS) from pathogenic bacteria during E. sinensis culture.
View Article and Find Full Text PDFKnee
January 2025
Department of Radiology, Keio University School of Medicine, Shinjuku, Tokyo, Japan.
Background: Long-leg alignment and joint line obliquity have traditionally been assessed using two-dimensional (2D) radiography, but the accuracy of this measurement has remained unclear. This study aimed to evaluate the accuracy of 2D measurements of lateral distal femoral angle (LDFA) and medial proximal tibial angle (MPTA) using upright three-dimensional (3D) computed tomography (CT).
Methods: This study involved 66 knees from 38 patients (34 women, four men) with knee osteoarthritis (OA), categorized by Kellgren-Lawrence (KL) grade.
BMJ Case Rep
January 2025
Orthopaedic Surgery and Sports Medicine, Amsterdam UMC Location AMC, Amsterdam, The Netherlands.
A patient in his 40s presented at the outpatient clinic with sudden pain and swelling over his medial malleolus, 16 weeks after he had undergone osteoperiosteal autografting with a medial malleolar osteotomy for his tertiary osteochondral lesion of the talus. Postoperatively, the patient was treated using the regular evidence-based rehabilitation protocol of 5 weeks of non-weight-bearing and 5 weeks of partial weight-bearing. However, after the confirmed radiological union the patient experienced an acute on chronic stress fracture through the osteotomy line.
View Article and Find Full Text PDFSpine J
January 2025
Center for Muscle and Joint Health, Department of Sport Sciences and Clinical Biomechanics, University of Southern Denmark; Chiropractic Knowledge Hub, University of Southern Denmark, Denmark. Electronic address:
Background Context: Recumbent MRI is the most widely used image modality in people with low back pain (LBP), however, it has been proposed that upright (standing) MRI has advantages over recumbent MRI because of its ability to assess the effects of being weight-bearing. It has been suggested that this produces systematic differences in MRI parameters and differences in the correlation between MRI parameters and pain or disability in patients thus, potentially adding clinically helpful information.
Purpose: This paper aims to review and summarize the available empirical evidence for or against these two hypotheses.
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