Two molecule-bridged bis(tetracyanoiron) complexes [(NC)(4)Fe(BL)Fe(CN)(4)](n)()(-), BL = 2,2'-bipyrimidine (bpym) and 3,6-bis(2-pyridyl)-1,2,4,5-tetrazine (bptz), were studied by EPR, UV/vis/near-IR and IR spectroelectrochemistry (n = 2-5) in aprotic media. Following these results, the Fe(2)(2.5) formulation is the correct valence description for the metal centers in the bptz-bridged trianion (K(c) = 10(14.6) in CH(3)CN), whereas the localized Fe(III)/Fe(II) formulation is appropriate for the bpym-bridged system (K(c) = 10(5.4) in CH(3)CN and 10(6.4) in CH(2)Cl(2)). In contrast to common perception, the larger tetrazine-bridged system with the longer metal-metal distance exhibits much stronger metal-metal coupling than the bpym-bridged analogue, a consequence of the very low lying pi LUMO of tetrazines with high MO coefficients at the coordinating nitrogen centers.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/ic990249l | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bots in white coats: are large language models the future of patient education? a multi-center cross-sectional analysis.
Int J Surg
January 2025
Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Munich, Germany.
Objectives: Every year, around 300 million surgeries are conducted worldwide, with an estimated 4.2 million deaths occurring within 30 days after surgery. Adequate patient education is crucial, but often falls short due to the stress patients experience before surgery.
View Article and Find Full Text PDFDevelopment and optimization of raloxifene hydrochloride loaded lipid nanocapsule based hydrogel for transdermal delivery.
Ther Deliv
January 2025
Institute of Pharmaceutical Research, GLA University, Mathura, India.
Aim: Development and optimization of raloxifene hydrochloride loaded lipid nanocapsule hydrogel for transdermal delivery.
Method: A 3 Box-Behnken Design and numerical optimization was performed to obtain the optimized formulation. Subsequently, the optimized raloxifene hydrochloride loaded lipid nanocapsule was developed using phase inversion temperature and characterized for physicochemical properties.
Health literacy status and associated factors among residents in Anhui Province, China: a cross-sectional study.
Front Public Health
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, China.
Background: Health literacy (HL) is a critical determinant of health outcomes. Improving HL stands as one of the most essential, cost-effective, and efficacious strategies for enhancing the overall health of the population. This study aims to analyze the status of HL among urban and rural residents in Anhui Province, explore the associated factors, and provide a scientific basis for the formulation of targeted health education and promotion strategies.
View Article and Find Full Text PDFThe Prognostic Value of Peripheral Blood Inflammatory Markers in Hepatocellular Carcinoma Treated with Lenvatinib Combined with PD-1 Inhibitors.
J Hepatocell Carcinoma
January 2025
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People's Republic of China.
Purpose: To investigate the prognostic value of inflammatory indexes based on peripheral blood cells in unresectable hepatocellular carcinoma (HCC) patients treated with Lenvatinib combined with PD-1 inhibitors.
Methods: This study retrospectively collected baseline inflammatory indexes from HCC patients received Lenvatinib and PD-1 inhibitor-based combination therapy at the Cancer Hospital of the Chinese Academy of Medical Sciences between October 2018 and October 2021. The optimal threshold values for inflammatory indexes determined using X-tile.
A focus on chasing pharmaceutical polymorphs to design better oral drug formulations.
Chem Sci
January 2025
Yusuf Hamied Department of Chemistry, University of Cambridge Lensfield Road Cambridge CB2 1EW UK
The pharmaceutical industry cares about reducing toxic side effects of drugs in oral formulation. The best solution is to reduce the drug dose. To do so, drugs are required to have high aqueous solubility to ensure good bioavailability.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!