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Future directions in psychiatric neurosurgery: Proceedings of the 2022 American Society for Stereotactic and Functional Neurosurgery meeting on surgical neuromodulation for psychiatric disorders.
Brain Stimul
June 2023
Department of Neurosurgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Objective: Despite advances in the treatment of psychiatric diseases, currently available therapies do not provide sufficient and durable relief for as many as 30-40% of patients. Neuromodulation, including deep brain stimulation (DBS), has emerged as a potential therapy for persistent disabling disease, however it has not yet gained widespread adoption. In 2016, the American Society for Stereotactic and Functional Neurosurgery (ASSFN) convened a meeting with leaders in the field to discuss a roadmap for the path forward.
View Article and Find Full Text PDFPatient-Reported Outcomes and Predictive Factors following Focused Ultrasound Thalamotomy for Essential Tremor.
Stereotact Funct Neurosurg
January 2023
Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia, USA.
Introduction: The objectives of this study were to determine long-term patient-reported outcomes with magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy for medication-refractory essential tremor (ET) and to identify risk factors for a poor clinical outcome.
Methods: We administered a telephone or mail-in survey to patients who consecutively underwent unilateral MRgFUS thalamotomy for ET at our institution over an 8-year period. Patients were asked to self-report measures of hand tremor improvement, degree of overall postprocedure improvement, activities of daily life, side effects, and willingness to undergo the procedure again.
Automated analysis of cortical volume loss predicts seizure outcomes after frontal lobectomy.
Epilepsia
May 2021
Cleveland Clinic Epilepsy Center, Cleveland Clinic Foundation, Cleveland, OH, USA.
Article Synopsis
- Some patients who have surgery to remove part of their brain (frontal lobectomy) don't have as many seizures compared to those who have other types of brain surgery like temporal lobectomy.
- Researchers studied 90 patients who had this surgery to see if looking at brain scans (MRIs) before surgery could help predict if they would be free of seizures afterwards.
- They found that a lot of important information about the brain's size and shape from MRIs could actually help predict if a patient would be seizure-free after the surgery.
Deep brain stimulation (DBS) is frequently described as a 'reversible' medical treatment, and the reversibility of DBS is often cited as an important reason for preferring it to brain lesioning procedures as a last resort treatment modality for patients suffering from treatment-refractory conditions. Despite its widespread acceptance, the claim that DBS is reversible has recently come under attack. Critics have pointed out that data are beginning to suggest that there can be non-stimulation-dependent effects of DBS.
View Article and Find Full Text PDFDr. Robert G. Heath: a controversial figure in the history of deep brain stimulation.
Neurosurg Focus
September 2017
Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
The history of psychosurgery is filled with tales of researchers pushing the boundaries of science and ethics. These stories often create a dark historical framework for some of the most important medical and surgical advancements. Dr.
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