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Religion as a Functional Equivalent of Medicine: Religious Experiences of Family Caregivers of People with Chronic Illnesses in Addis Ababa, Ethiopia.
J Relig Health
January 2025
Department of Sociology, Addis Ababa University, Addis Ababa, Ethiopia.
This article details the religious experiences of family caregivers in living with and caring for people with chronic illnesses in Addis Ababa, Ethiopia. This phenomenological study conducted in-depth interviews with 20 family caregivers recruited from Tikur Anbessa Specialized Hospital, who accompanied their loved ones during medical appointments or hospital stays. It used a thematic analysis to analyze the collected data.
View Article and Find Full Text PDFRegulatory Roles of SWI/SNF Chromatin Remodeling Complexes in Immune Response and Inflammatory Diseases.
Clin Rev Allergy Immunol
December 2024
Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, 310009, People's Republic of China.
The switch/sucrose non-fermentable (SWI/SNF) chromatin remodeling complexes (also referred to as BAF complexes) are composed of multiple subunits, which regulate the nucleosome translocation and chromatin accessibility. In recent years, significant advancements have been made in understanding mutated genes encoding subunits of the SWI/SNF complexes in cancer biology. Nevertheless, the role of SWI/SNF complexes in immune response and inflammatory diseases continues to attract significant attention.
View Article and Find Full Text PDFCAR T-Cell Therapy for Rheumatic Diseases: What Does the Future Hold?
BioDrugs
December 2024
Rheumatology Department, Strasbourg University Hospital, 1 Avenue Molière, 67000, Strasbourg, France.
Chimeric antigen receptor (CAR) T-cell therapy, initially successful in treating hematological malignancies, is emerging as a potential treatment for autoimmune diseases, including rheumatic conditions. CAR T cells, engineered to target and eliminate autoreactive B cells, offer a novel approach to managing diseases like systemic lupus erythematosus (SLE), systemic sclerosis (SSc), and inflammatory myopathies, where B cells play a pivotal role in disease pathology. Early case reports have demonstrated promising results, with patients achieving significant disease remission, normalization of serological markers, and the ability to discontinue traditional immunosuppressive therapies, which supported the initiation of several clinical trials.
View Article and Find Full Text PDFMeasuring visual ability in linguistically diverse populations.
Behav Res Methods
December 2024
Department of Psychology, Vanderbilt University, Nashville, TN, USA.
Measurement of object recognition (OR) ability could predict learning and success in real-world settings, and there is hope that it may reduce bias often observed in cognitive tests. Although the measurement of visual OR is not expected to be influenced by the language of participants or the language of instructions, these assumptions remain largely untested. Here, we address the challenges of measuring OR abilities across linguistically diverse populations.
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