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Pediatric Dialysis: Ethical Dilemmas Faced by Pediatric Intensive Care Nurses.
Nephrol Nurs J
January 2025
Research Associate Professor of Biostatistics, Department of Biostatics and Computational Biology, University of Rochester Medical Center, Rochester, NY.
Whether pediatric dialysis is morally obligatory is an ethical issue. The study's aim was to understand neonatal and pediatric intensive care unit (ICU) nurses' beliefs regarding the ethical use of pediatric dialysis. A single center study was conducted using theoretical and case-based surveys.
View Article and Find Full Text PDFArtificial womb technology - A more physiologic solution to treating extreme prematurity.
Eur J Obstet Gynecol Reprod Biol X
March 2025
Department of Surgery, Duke University, Durham, NC, USA.
Treatment of extreme premature infants (EPI) is limited by developmental immaturity primarily of the lung. A paradigm shift towards a more physiologic treatment of EPI as fetal neonates or , by keeping them in a womb-like environment to allow continued organ maturation, is the rationale for artificial womb technology. In this review, we discuss the artificial placenta and womb technology, it's rationale, the history of its development, the most recent preclinical models described in the literature and finally pertinent ethical considerations.
View Article and Find Full Text PDFPrevalence of Idiopathic Macular Hole in a Specialized Ophthalmological Referral Center: A Retrospective Cross-Sectional Study (2018-2022).
Cureus
December 2024
Ophthalmology Department, University of Kansas School of Medicine, Kansas City, USA.
Background: An idiopathic macular hole (IMH) is a foveal opening in the neurosensory retina caused by perifoveal vitreomacular traction and detachment. IMH prevalence varies considerably across populations, highlighting a need for further investigation, especially in underrepresented groups such as Hispanics.
Methods: This retrospective, descriptive, cross-sectional study analyzed IMH prevalence in a Hispanic population over four years.
Helminth extracellular vesicles co-opt host monocytes to drive T cell anergy.
J Extracell Vesicles
January 2025
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Parasitic helminths secrete extracellular vesicles (EVs) into their host tissues to modulate immune responses, but the underlying mechanisms are poorly understood. We demonstrate that Ascaris EVs are efficiently internalised by monocytes in human peripheral blood mononuclear cells and increase the percentage of classical monocytes. Furthermore, EV treatment of monocytes induced a novel anti-inflammatory phenotype characterised by CD14, CD16, CC chemokine receptor 2 (CCR2) and programmed death-ligand 1 (PD-L1) cells.
View Article and Find Full Text PDFInfrared thermography in clinical practice: a literature review.
Eur J Med Res
January 2025
China Medical University, Shenyang, Liaoning, China.
Background: Infrared thermography technology is a diagnostic imaging modality that converts temperature information on the surface of the human body into visualised thermograms. This technology has the capacity to intuitively detect the presence of certain abnormal conditions or foci in the human body. In recent years, the application of this technology in medicine has become increasingly extensive, especially in the areas of auxiliary diagnosis and early screening of diseases.
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