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Idiopathic unilateral complete oculomotor nerve palsy: a case report of diagnostic quandary.
Ann Med Surg (Lond)
October 2024
KIST Medical College and Teaching Hospital, Gwarko, Lalitpur, Nepal.
Introduction And Importance: When compared to other cranial nerve palsies idiopathic unilateral oculomotor nerve palsy with pupillary sparing is one of the least noted neurological conditions. Moreover, there lies a series of diagnostic dilemmas to come into a final diagnosis resulting in several array of clinical investigations. Hence, there is a delay in prompt management.
View Article and Find Full Text PDFAcute Aortic Dissection during Pregnancy: Hideous Clinical Quandaries with Young Lives on the Line-The Role of Hereditary Genetic Syndromes.
J Clin Med
August 2024
Department of Cardiac Surgery, Rostock Heart Center, University Medical Center Rostock, 18057 Rostock, Germany.
Acute aortic dissection is a rare but frequently fatal aortic catastrophe with high morbidity and mortality. Especially in pregnant patients, acute dissection is often misdiagnosed putting two lives on the line. Due to its scarcity, only case reports have been reported.
View Article and Find Full Text PDFModerate aortic stenosis: Navigating the uncharted.
Echocardiography
June 2024
Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Aortic stenosis (AS) stands as the most common valvular heart disease in developed countries and is characterized by progressive narrowing of the aortic valve orifice resulting in elevated transvalvular flow resistance, left ventricular hypertrophy, and progressive increased risk of heart failure and sudden death. This narrative review explores clinical challenges and evolving perspectives in moderate AS, where discrepancies between aortic valve area and pressure gradient measurements may pose diagnostic and therapeutic quandaries. Transthoracic echocardiography is the first-line imaging modality for AS evaluation, yet cases of discordance may require the application of ancillary noninvasive diagnostic modalities.
View Article and Find Full Text PDFDiagnosing Cystic Fibrosis in the 21st Century-A Complex and Challenging Task.
Diagnostics (Basel)
April 2024
Department of Preventive Medicine and Interdisciplinarity-Public Health and Health Management, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iaṣi, Romania.
Cystic fibrosis (CF) is a chronic and potentially life-threatening condition, wherein timely diagnosis assumes paramount significance for the prompt initiation of therapeutic interventions, thereby ameliorating pulmonary function, addressing nutritional deficits, averting complications, mitigating morbidity, and ultimately enhancing the quality of life and extending longevity. This review aims to amalgamate existing knowledge to provide a comprehensive appraisal of contemporary diagnostic modalities pertinent to CF in the 21st century. Deliberations encompass discrete delineations of each diagnostic modality and the elucidation of potential diagnostic quandaries encountered in select instances, as well as the delineation of genotype-phenotype correlations germane to genetic counseling endeavors.
View Article and Find Full Text PDFCrossing of the Hu line by Neolithic population in response to seesaw precipitation changes in China.
Sci Bull (Beijing)
April 2022
Key Laboratory of Cenozoic Geology and Environment, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing 100029, China.
How various peoples crossed geographical barriers, were affected by climate change and human-made technologies comprise some of the most interesting quandaries in the history of cultures. This paper considers the Hu line, which is a major boundary between population centres and different environments in China. The boundary became evident approximately 11,400 years ago; however, evidence suggests that people crossed through at 5200, 3800, and 2800 cal a BP, facilitating the increases of the trans-Eurasian exchange.
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