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The impact of the COVID-19 pandemic on patients with nonmalignant and malignant dermatologic conditions.
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Human neural stem cells directly programmed from peripheral blood show functional integration into the adult mouse brain.
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Institute of Reconstructive Neurobiology, University of Bonn Medical Faculty and University Hospital Bonn, Venusberg-Campus 1, Bonn, 53127, Germany.
Transplantation of induced pluripotent stem cell-derived neural cells represents a promising strategy for treating neurodegenerative diseases. However, reprogramming of somatic cells and their subsequent neural differentiation is complex and time-consuming, thereby impeding autologous applications. Recently, direct transcription factor-based conversion of blood cells into induced neural stem cells (iNSCs) has emerged as a potential alternative.
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