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Beyond Stocks and Surges: The Demographic Impact of the Unauthorized Immigrant Population in the United States.
Popul Dev Rev
December 2024
Population Research Institute, The Pennsylvania State University, University Park, 315J Welch Building 137 Fischer Road, PA 16802, Pennsylvania, USA.
Stock estimates of the US unauthorized foreign-born population are routinely published, but less is known about this population's dynamics. Using a series of residual estimates based on 2000 Census and 2001-2022 American Community Survey (ACS), I estimate the components of change for the unauthorized immigrant population from 2000 to 2022 by region and country of origin. Further, I develop and present novel measures of expected duration in unauthorized status and demographic impact of unauthorized entries (i.
View Article and Find Full Text PDFCardiovascular Disease Risk in South Asians in the Baylor Scott and White Health DILWALE Registry.
JACC Adv
December 2024
Johns Hopkins Department of Internal Medicine, Baltimore, Maryland, USA.
Background: Despite implementation of preventive interventions targeting cardiovascular disease (CVD), atherosclerotic CVD (ASCVD) remains a major public health concern in the South Asian (SA) population.
Objectives: The purpose of this study was to assess the risk factor prevalence and ASCVD outcomes in SA population in the United States.
Methods: The DIL Wellness and Arterial health Longitudinal Evaluation registry collected data retrospectively on SA adult patients receiving care in the Baylor Scott & White Healthcare system.
Unlabelled: The increased rate of anterior cruciate ligament (ACL) tears has led to a greater number of revisions. Revision surgery can be performed in one or two stages. Single-stage revision ACL reconstruction (ssRACLR) may be performed when prior tunnels can be re-used or bypassed whereas a two-stage procedure is indicated when bone grafting of dilated tunnels prior to revision is necessary.
View Article and Find Full Text PDFAutophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity.
Nat Metab
January 2025
CECAD Excellence Center, University of Cologne, Cologne, Germany.
Dysfunctions in autophagy, a cellular mechanism for breaking down components within lysosomes, often lead to neurodegeneration. The specific mechanisms underlying neuronal vulnerability due to autophagy dysfunction remain elusive. Here we show that autophagy contributes to cerebellar Purkinje cell (PC) survival by safeguarding their glycolytic activity.
View Article and Find Full Text PDFDNA is subject to continual damage, leaving each cell with thousands of individual DNA lesions at any given moment. The efficiency of DNA repair means that most known classes of lesion have a half-life of minutes to hours, but the extent to which DNA damage can persist for longer durations remains unknown. Here, using high-resolution phylogenetic trees from 89 donors, we identified mutations arising from 818 DNA lesions that persisted across multiple cell cycles in normal human stem cells from blood, liver and bronchial epithelium.
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