Similar Publications
Multi-omics analysis of druggable genes to facilitate Alzheimer's disease therapy: A multi-cohort machine learning study.
J Prev Alzheimers Dis
March 2025
Department of Pathophysiology School of Basic Medicine Key Laboratory of Education Ministry/Hubei Province of China for Neurological Disorders Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:
Background: The swift rise in the prevalence of Alzheimer's disease (AD) alongside its significant societal and economic impact has created a pressing demand for effective interventions and treatments. However, there are no available treatments that can modify the progression of the disease.
Methods: Eight AD brain tissues datasets and three blood datasets were obtained.
Effect of optimal lesion preparation prior to implantation of a magnesium-based bioresorbable scaffold: 12-month results of the OPTIMIS study.
Cardiovasc Revasc Med
March 2025
Department of Cardiology, Odense University Hospital, Odense, Denmark; University of Southern Denmark, Odense, Denmark.
Background: Lumen reduction after bioresorbable scaffold implantation has been reported. This study aimed to assess the influence of pre-dilatation with a scoring balloon versus a standard non-compliant balloon prior to implanting a magnesium-based Magmaris bioresorbable scaffold (MgBRS) on lumen measurements using optical coherence tomography (OCT) and on clinical outcomes after 12 months.
Method: In the OPTIMIS-study (Optimal lesion preparation before implantation of a MgBRS in patients with coronary artery stenosis), patients were randomly assigned to pre-dilatation with a scoring balloon or a standard non-compliant balloon before MgBRS implantation.
Fruit, vegetables and discretionary food intake in Australian adults: Past trends and predicted progress towards population preventive health targets for 2030.
Aust N Z J Public Health
February 2025
Commonwealth Scientific and Industrial Research Organisation (CSIRO) Health & Biosecurity, Adelaide, South Australia 5000, Australia. Electronic address:
Objective: In Australia, 'improving access to and the consumption of a healthy diet' is a focus in the National Preventive Health Strategy. The objective of this paper is to describe the past trends and future projections of population intakes against the Strategy's targets of increasing fruit consumption to 2 servings per day; increasing vegetables to 5 servings; and reducing discretionary foods to <20% of total energy by 2030.
Methods: Self-reported intake data were available from an online survey of 275,170 Australian adults collected between 2015 and 2023.
[Not Available].
Z Evid Fortbild Qual Gesundhwes
March 2025
Zentrum für Psychische Gesundheit, Klinik und Poliklinik für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie, Universitätsklinikum Würzburg, Würzburg, Deutschland; Deutsches Zentrum für Präventionsforschung und Psychische Gesundheit, Universität Würzburg, Würzburg, Deutschland.
[Merkel cell carcinoma: An update].
Bull Cancer
March 2025
Dermatologie, CHU de Tours, Tours, France; Réseau CARADERM, France.
Merkel cell carcinoma (MCC) is a rare skin cancer that mainly affects the elderly, and whose incidence is increasing. Although the exact origin of this cancer remains uncertain, research in recent years has revealed that MCC develops through two oncogenesis pathways: virally induced by the Merkel polyomavirus (80% of cases) and induced by mutations linked to ultraviolet rays (20% of cases). MCC is an aggressive cancer, with a high mortality rate and limited therapeutic options in advanced stage.
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