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Bassoon, Presynaptic Scaffolding Protein: Narrative Review in Health and Disease.
Eur J Neurosci
March 2025
Parkinson's Disease and Movement Disorders Clinic, Bangalore, India.
The release of synaptic vesicles (SVs) at the synaptic junction is a complex process involving various specialized proteins that work in unison. Among these, Bassoon has emerged as a significant protein, particularly noted for its association with various neurological and aging-related diseases. Due to its structural and functional roles, Bassoon has become a focus of recent research, especially in understanding its implications in neurodegenerative and psychiatric disorders.
View Article and Find Full Text PDFNeurodevelopmental and psychiatric conditions in 600 Swedish children with the avoidant/restrictive food intake disorder phenotype.
J Child Psychol Psychiatry
March 2025
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Background: Avoidant restrictive food intake disorder (ARFID) is a feeding and eating disorder characterized by extremely restricted dietary variety and/or quantity resulting in serious consequences for physical health and psychosocial functioning. ARFID often co-occurs with neurodevelopmental conditions (NDCs) and psychiatric conditions, but previous data are mostly limited to small clinical samples examining a narrow range of conditions. Here, we examined NDCs and psychiatric conditions in a large, population-based group of children with ARFID.
View Article and Find Full Text PDFA reflection on Arnold Caplan, the father of MSC.
Best Pract Res Clin Haematol
December 2024
Departments of Pathology, Biomedical Engineering, and Macromolecular Science, Case Western Reserve University, USA. Electronic address:
Arnold Caplan was the father of MSC, mesenchymal stem cells. His pioneering efforts have led to significant advances in the utilization of mesenchymal stem cells for the treatment of a wide variety of clinical diseases. This reflection provides some insight into Arnold's commitment to education and research regarding mesenchymal stem cells.
View Article and Find Full Text PDFStandardizing nurse practitioner clinical education: The Cognitive Preceptorship Model.
J Prof Nurs
March 2025
University of Memphis, Loewenberg College of Nursing, United States of America. Electronic address:
Background: Though preparing autonomous advanced nursing providers who are ready to care for complex clients in a variety of settings after graduation is necessary to achieve clinical competence, NP clinical education activities used to achieve competencies are greatly variable and hard to measure. The quality of students' clinical experiences impacts students' achievement of clinical competence (CC) and achieving CC is important for the NPs to successfully transition to practice after graduation.
Aim: The purpose of this project is to apply the Cognitive Preceptorship Model (CPM) to design, describe, and explain the clinical activities that are NP role-specific, that scaffold from the American Association of Colleges of Nursing (AACN), and National Organization of Nurse Practitioner Faculties (NONPF) competencies and that help NP students achieve competencies.
Role of exosomes in regulating ferroptosis of tumor cells.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
October 2024
Medical Research Experimental Center, Shaanxi University of Chinese Medicine, Xianyang Shaanxi 712046, China.
Exosomes are nanoscale extracellular vesicles widely present in various body fluids. They carry a variety of substances, including proteins, lipids, and nucleic acids, and play significant roles in the body by participating in immune regulation, intercellular signal transduction, and the transport of proteins and nucleic acids. Exosomes can regulate tumor development and drug resistance by modulating ferroptosis.
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