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Trials and Tribulations: Responses of ChatGPT to Patient Questions About Kidney Transplantation.
Transplantation
October 2024
Department of Surgery, NYU Grossman School of Medicine, New York, NY.
Trials and tribulations of managing pediatric and adolescent asthma.
Ann Allergy Asthma Immunol
January 2024
Department of Pediatrics, The University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, Tennessee. Electronic address:
Optimizing cord management for each preterm baby - Challenges of collating individual participant data and recommendations for future collaborative research.
Semin Perinatol
June 2023
MPH FAHMS FHEA, University of Sydney, Australia.
The optimal cord management strategy at birth for each preterm baby is still unknown, despite more than 100 randomized controlled trials (RCTs) undertaken on this question. To address this, we brought together all RCTs examining cord management strategies at preterm birth in the iCOMP (individual participant data on COrd Management at Preterm birth) Collaboration, to perform an individual participant data network meta-analysis. In this paper, we describe the trials and tribulations around obtaining individual participant data to resolve controversies around cord clamping, and we derive key recommendations for future collaborative research in perinatology.
View Article and Find Full Text PDFCoronavirus Disease 2019 Vaccine Trials (and Tribulations): How to Improve the Process of Clinical Trials in a Pandemic.
Clin Infect Dis
August 2022
Division of Infectious Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Vaccine clinical trials have been essential to developing effective severe acute respiratory syndrome coronavirus 2 vaccines. The challenges of supply chain disruptions, infection control, study designs, and participant factors that affect trial procedures are reviewed, with specific solutions to streamline the clinical trial process.
View Article and Find Full Text PDFThe Trials and Tribulations of Selecting Comparison Groups in Randomized Trials of Nonpharmacological Complementary and Integrative Health Interventions.
J Altern Complement Med
June 2020
Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA, USA.
For over two decades, Editorial Board member Karen Sherman, PhD has been among the most respected clinical trialists in complementary and integrative health research. The epidemiologist and Senior Researcher at Kaiser Permanente Washington Health Research Institute has focused on pain conditions and has led or been part of teams exploring the roles of such therapies as yoga, acupuncture, mind-body and manual therapies. In this Invited Commentary, Sherman shares wisdom gleaned from the process: trial designs, principles for selecting controls, benefits and liabilities of placebo and sham controls, attention controls, usual care controls, and more.
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