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PLoS One
January 2025
INSERM U1151, Université Paris Cité, Centre de Références Maladies Rares Mucoviscidose et Maladies Apparentées, Hôpital Necker Enfants Malades, Paris, France.
The Cystic Fibrosis (CF) Impact Questionnaire (CF-IQ) was qualitatively developed to assess the impact of CF in the context of treatment advancements and increased longevity. This study reports the CF-IQ validation. In this noninterventional validation study, people with CF completed the 40-item CF-IQ and validating patient-reported outcome measures (PROMs) via electronic diaries at enrollment (baseline) and at the 4-week follow-up.
View Article and Find Full Text PDFEntropy (Basel)
January 2025
Science, Mathematics and Technology (SMT) Cluster, Singapore University of Technology and Design, Singapore 487372, Singapore.
In this paper, we construct -ary codes for correcting a burst of at most deletions, where t,q≥2 are arbitrarily fixed positive integers. We consider two scenarios of error correction: the classical error correcting codes, which recover each codeword from one read (channel output), and the reconstruction codes, which allow to recover each codeword from multiple channel reads. For the first scenario, our construction has redundancy logn+8loglogn+o(loglogn) bits, encoding complexity O(q7tn(logn)3) and decoding complexity O(nlogn).
View Article and Find Full Text PDFEntropy (Basel)
December 2024
Department of Stochastics, Institute of Mathematics, Budapest University of Technology and Economics, Muegyetem rkp. 3, H ep, 5 em, 1521 Budapest, Hungary.
The paper gives a wide range, uniform, local approximation of symmetric binomial distribution. The result clearly shows how one has to modify the classical de Moivre-Laplace normal approximation in order to give an estimate at the tail as well as to minimize the relative error.
View Article and Find Full Text PDFJ Phys Chem A
January 2025
Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, Odense M DK-5230, Denmark.
Quantum computing presents a promising avenue for solving complex problems, particularly in quantum chemistry, where it could accelerate the computation of molecular properties and excited states. This work focuses on computing excitation energies with hybrid quantum-classical algorithms for near-term quantum devices, combining the quantum linear response (qLR) method with a polarizable embedding (PE) environment. We employ the self-consistent operator manifold of quantum linear response (q-sc-LR) on top of a unitary coupled cluster (UCC) wave function in combination with a Davidson solver.
View Article and Find Full Text PDFIntegr Environ Assess Manag
January 2025
DEBtox Research, Stevensweert, The Netherlands.
Environmental risk assessment of chemicals (ERA) relies on single-species laboratory testing to establish the toxic properties of a compound. However, ERA is not concerned with toxicity under laboratory conditions: it needs to assess the impacts of the compound in the real world. Data-driven statistical analyses (e.
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