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Predicting a strongly positive fluid balance in critically ill patients with acute kidney injury: A multicentre, international study.
J Crit Care
January 2025
Department of Intensive Care, Austin Hospital, Heidelberg, VIC, Australia; Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Background: In critically ill patients with acute kidney injury (AKI), a fluid balance (FB) > 2 L at 72 h after AKI diagnosis is associated with adverse outcomes. Identification of patients at high-risk for such fluid accumulation may help prevent it.
Methods: We used Australian electronic medical record (EMR)-based clinical data to develop the "AKI-FB risk score", validated it in a British cohort and used it to predict a positive FB >2 L at 72 h after AKI diagnosis.
Prognostic value of the Global Leadership Initiative on Malnutrition criteria including systemic inflammation in patients with advanced cancer.
Br J Nutr
January 2025
Academic Unit of Surgery, School of Medicine, University of Glasgow, New Lister Building, Royal Infirmary, GlasgowG31 2ER, Scotland, UK.
An assessment of systemic inflammation and nutritional status may form the basis of a framework to examine the prognostic value of cachexia in patients with advanced cancer. The objective of the study was to examine the prognostic value of the Global Leadership Initiative on Malnutrition criteria, including BMI, weight loss (WL) and systemic inflammation (as measured by the modified Glasgow Prognostic Score (mGPS)), in advanced cancer patients. Three criteria were examined in a combined cohort of patients with advanced cancer, and their relationship with survival was examined using Cox regression methods.
View Article and Find Full Text PDFPregnancy does not affect liver chemistries in metabolic dysfunction-associated steatotic liver disease.
Hepatol Commun
December 2024
Division of Gastroenterology, Department of Medicine, Hepatology, and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Gut Microbial Signatures in Pediatric Crohn's Disease Vary According to Disease Activity Measures and Are Influenced by Proxies of Gastrointestinal Transit Time: An ImageKids Study.
Inflamm Bowel Dis
October 2024
Human Nutrition, School of Medicine, Dentistry & Nursing, University of Glasgow, New Lister Building, Glasgow Royal Infirmary, Glasgow G31 2ER, UK.
Introduction: We investigated relationships between disease activity measures and the gut microbiome in children with Crohn's disease (CD) and how these were confounded by gastrointestinal transit time.
Methods: Microbiome was profiled (16S rRNA sequencing) in feces from 196 children with CD. Sixty participants also provided samples after 18 months.
Efficacy, Safety and Acceptability of a Very-Low-Energy Diet in Adolescents with Obesity: A Fast Track to Health Sub-Study.
Nutrients
September 2024
Sydney Medical School, The University of Sydney, Westmead, NSW 2145, Australia.
Article Synopsis
- * 134 participants lost an average of 5.5 kg during the program, though 95% reported experiencing side-effects, most commonly hunger and fatigue.
- * While many found the diet helpful for weight loss, they also noted its restrictive nature and taste issues; future research may identify which adolescents benefit the most from such diets.
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