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[Neuraxitis in critical exanthema: description of a case].

Pediatr Med Chir

October 1992

Divisione Pediatria, Ospedale di Chiavari Genova, Italia.

In this work the Authors describe the case of a 16-month-old child, who presented neuraxitis infection of cerebellum, during exanthem subitum. From the present etiological considerations about exanthem subitum, referable to human herpes virus type 6, the Authors stress the usefulness of executing the dosage of anti-HHV6 antibodies in all the cases of exanthem subitum and in all febrile convulsions, because it is possible to have atypical clinic forms of VI disease, without exanthem.

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Seven cases of acute neuraxitis due to Coxsackie B3, 2 to mumps, 1 to measles, and 1 to influenza B observed in the province of Alessandria between Jan. 1975 and July 1977 are described. In the coxsackie cases, blood chemistry and clinical examinations were coupled with determination of serum levels of complement fixing, haemagglutin-inhibiting and neutralising antibodies on two successive specimens, isolation of virus from cerebrospinal fluid and faeces, and, in one case, from a cerebral biopsy specimen, and determination of cerebrospinal fluid IgA, IgG, and IgM.

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