AI Article Synopsis
- Sentinel lymph nodes are the first nodes that filter out tumor cells, and their identification helps guide how extensive lymph node removal should be during surgery.
- A study looked back at 41 patients who had esophageal surgery to understand where these sentinel nodes were located and found that nearly half of the metastatic nodes corresponded with the tumor sites.
- The research revealed that while most sentinel nodes were in nearby areas, some were found farther away, indicating that their distribution can vary based on the tumor's location in the esophagus.
Article Abstract
Sentinel lymph nodes are the first draining nodes that contain tumor cells. Identification of sentinel nodes may help to determine the suitable extent of lymphadenectoy. To assess the location of sentinel lymph nodes, a series of 41 patients with single and two metastatic lymph nodes who underwent esophagectomy and 3-field lymphadenectomy between 1991 and 1999 were investigated retrospectively. Only 29 (47.5%) of 61 metastatic nodes showed correspondence between the tumor site and the regional metastatic lymph nodes by routine histologic examination. In the patients with tumors in the upper and middle thoracic esophagus, metastatic lymph nodes were distributed in the cervix, mediastinum and abdomen. Although sentinel nodes were limited to the regional and adjusting compartments in 82%, nodes were found beyond the adjusting compartments in 18%. The sentinel nodes were broadly distributed depending on the location of the tumor in esophageal cancer.
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| http://dx.doi.org/10.1272/jnms.68.393 | DOI Listing |
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