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Progress toward eliminating TB and HIV deaths in Brazil, 2001-2015: a spatial assessment.
BMC Med
September 2018
Institute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave Suite 600, Seattle, WA, 98121, USA.
Background: Brazil has high burdens of tuberculosis (TB) and HIV, as previously estimated for the 26 states and the Federal District, as well as high levels of inequality in social and health indicators. We improved the geographic detail of burden estimation by modelling deaths due to TB and HIV and TB case fatality ratios for the more than 5400 municipalities in Brazil.
Methods: This ecological study used vital registration data from the national mortality information system and TB case notifications from the national communicable disease notification system from 2001 to 2015.
Autism Spectrum Disorder, Developmental and Psychiatric Features in 16p11.2 Duplication.
J Autism Dev Disord
August 2016
Developmental Medicine, Children's Hospital Boston/Harvard Medical School, Boston, MA, USA.
The 16p11.2 duplication (BP4-BP5) is associated with Autism Spectrum Disorder (ASD), although significant heterogeneity exists. Quantitative ASD, behavioral and neuropsychological measures and DSM-IV diagnoses in child and adult carriers were compared with familial non-carrier controls, and to published results from deletion carriers.
View Article and Find Full Text PDFMolecular epidemiology of human enterovirus 71 in the United Kingdom from 1998 to 2006.
J Clin Microbiol
October 2008
Infection and Immunology Unit, Guys and St Thomas' NHS Foundation Trust, 5th Floor, North Wing, St Thomas' Hospital, London SE1 7EH, United Kingdom.
The last decade witnessed a significant increase in epidemic activity of human enterovirus 71 (EV71) in the Western Pacific Region (WPR). In most European countries, this risk is unrecognized despite occasional cases of severe disease and two severe outbreaks in Eastern Europe 30 years ago. In this study we report the first examination of the molecular epidemiology of EV71 in the United Kingdom from 1998 to 2006.
View Article and Find Full Text PDFPesticide residues in food--acute dietary exposure.
Pest Manag Sci
April 2004
Animal and Plant Health Service, Department of Primary Industries, Brisbane, Qld, Australia.
Consumer risk assessment is a crucial step in the regulatory approval of pesticide use on food crops. Recently, an additional hurdle has been added to the formal consumer risk assessment process with the introduction of short-term intake or exposure assessment and a comparable short-term toxicity reference, the acute reference dose. Exposure to residues during one meal or over one day is important for short-term or acute intake.
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