The eastern and western diaryl ether portions of the macrocyclic bastadins, natural products from the marine sponge Ianthella sp., have been assembled as [CpRu]+ complexes. In an HPLC study, aminopropyl-functionalised silica was found as a very suitable stationary phase for the chromatographic separation of the different cationic ruthenium sandwich complexes. It is now possible for the first time to effectively monitor and purify [CpRu]+ complexes and to carry them through several synthetic steps.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/1521-3765(20010917)7:18<3961::aid-chem3961>3.0.co;2-s | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Nucleophilic Aromatic Substitution of Halobenzenes and Phenols with Catalysis by Arenophilic π Acids.
Acc Chem Res
August 2024
Key Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province, Department of Chemistry, School of Science and Research Center for Industries of the Future, Westlake University, Hangzhou, Zhejiang 310030, China.
ConspectusLewis π acids, particularly high-valent transition metals with vacant orbitals, can coordinate with unsaturated compounds such as alkynes and alkenes by means of π-bonding. The coordination enhances the electrophilicity of the bound compounds, thereby facilitating reactions─such as nucleophilic addition─that take place at the ligated carbon-carbon multiple bonds. This activation phenomenon occurs at the ligand rather than at the metal atom, and it has been extensively utilized in the development of catalytic methods.
View Article and Find Full Text PDFEvaluation of the Antiproliferative Properties of CpRu Complexes Containing N-Methylated Triazaphosphaadamantane Derivatives.
Bioinorg Chem Appl
September 2023
Centro de Química Estrutural, Institute of Molecular Sciences, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, Campo Grande 1749-016, Lisboa, Portugal.
Piano-stool-{CpRu} complexes containing 1,3,5-triaza-7-phosphaadamantane (PTA), -methyl-1,3,5-triaza-7-phosphaadamantane (mPTA), and 3,7-dimethyl-1,3,7-triaza-5-phosphabyciclo[3.3.1]nonane (dmoPTA) were evaluated as drugs against breast cancer.
View Article and Find Full Text PDFPiano-stool ruthenium(II) complexes with maleimide and phosphine or phosphite ligands: synthesis and activity against normal and cancer cells.
Dalton Trans
March 2023
University of Lodz, Faculty of Chemistry, Department of Organic Chemistry, Tamka 12, 91-403 Lodz, Poland.
In these studies, we designed and investigated cyto- and genotoxic potential of five ruthenium cyclopentadienyl complexes bearing different phosphine and phosphite ligands. All of the complexes were characterized with spectroscopic analysis (NMR, FT-IR, ESI-MS, UV-vis, fluorescence and XRD (for two compounds)). For biological studies, we used three types of cells - normal peripheral blood mononuclear (PBM) cells, leukemic HL-60 cells and doxorubicin-resistance HL-60 cells (HL-60/DR).
View Article and Find Full Text PDFSynthesis, structure, properties, and cytotoxicity of a (quinoline)RuCp complex.
Dalton Trans
January 2023
Michigan State University, Department of Chemistry, 578 S. Shaw Ln, East Lansing, MI 48824, USA.
A rare example of a structurally characterized metal quinoline complex was prepared using a non-covalent quinoline-based proteasome inhibitor (Quin1), and a related complex bearing an inactive quinoline ligand (Quin2) was also synthesized. The quinolines are prepared by a one-pot procedure involving titanium-catalyzed alkyne iminoamination and are bound to ruthenium by reaction with CpRu(NCMe) PF in CHCl. The arene of the quinoline is η-bonded to the ruthenium metal center.
View Article and Find Full Text PDF[Fp(CH)], [η-CpRu(CO)(CH)], and [η-CpOs(CO)(CH)]: A Complete Set of Group 8 Metal-Methane Complexes.
J Am Chem Soc
September 2022
School of Chemistry, University of New South Wales, Sydney, NSW 2052, Australia.
Here, we report the NMR spectroscopic analysis of the group 8 transition metal methane σ-complexes [η-CpM(CO)(CH)][Al(OC(CF))] (M = Fe, Ru) at -90 °C in the weakly coordinating solvent 1,1,1,3,3,3-hexafluoropropane. The iron(II)-methane complex has a H resonance at δ -4.27, a C resonance at δ -53.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!