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How are patient inputs considered in HTA? A thematic document analysis of NICE ultra-rare disease appraisals.
Eur J Health Econ
December 2024
Department of Health Policy, London School of Economics and Political Science, Houghton street, London, WC2A 2AE, UK.
Patient organisations are increasingly involved in HTA. Given this, it is important to understand what these organisations contribute and how their voices are accounted for in the decision-making process. This study characterises inputs from patient organisations and/or their nominated patient experts in technology appraisals for ultra-rare diseases in England and Wales and seeks to understand how these are considered in NICE final recommendations.
View Article and Find Full Text PDFPrevalence of Immature Survival Data for Anti-Cancer Drugs Presented to the National Institute for Health and Care Excellence between 2018-2022.
Value Health
December 2024
Sheffield Centre for Health and Related Research, University of Sheffield, Regent Court, 30 Regent Street, Sheffield, S1 4DA; Delta Hat Limited, Nottingham, UK.
Objectives: Between 2015 and 2017, 41% of NICE cancer single technology appraisal (STA) decisions relied upon immature survival data. This occurs when clinical trials that form the evidence base in support of new or existing technologies suffer from limited follow-up. During this period, NICE did not negatively recommend any cancer technologies that used immature data.
View Article and Find Full Text PDFCritical Appraisal of Evidence: Synthesis and Recommendations.
Am J Nurs
January 2025
Susan Farus-Brown is an associate professor at the Ohio University School of Nursing in Athens. Ellen Fineout-Overholt is national senior director, Evidence-Based Practice & Implementation Science, at Ascension in St. Louis. Deana Hays is an associate professor at Oakland University in Rochester, MI. Mary C. Zonsius is an associate professor at the Rush University College of Nursing in Chicago. Kerry A. Milner is a professor in the Davis and Henley College of Nursing at Sacred Heart University in Fairfield, CT. Contact author: Kerry A. Milner, The authors have disclosed no potential conflicts of interest, financial or otherwise.
This is the fifth article in a new series designed to provide readers with insight into educating nurses about evidence-based decision-making (EBDM). It builds on AJN's award-winning previous series-Evidence-Based Practice, Step by Step and EBP 2.0: Implementing and Sustaining Change (to access both series, go to https://links.
View Article and Find Full Text PDFThe impact of virtual reality applied in nurse education on students' clinical thinking: A systematic review.
Nurse Educ Today
December 2024
Department of Fundamental Nursing, School of Nursing, Jilin University, Changchun 130021, Jilin Province, PR China. Electronic address:
Objective: To summarise and compare the applications and effectiveness of virtual reality in cultivating clinical thinking among nursing students and to further analyse the active ingredients of virtual reality applications.
Design: Systematic review.
Review Methods: A systematic and comprehensive search of PubMed, Web of Science, Cochrane, Scopus, Embase, and CINAHL was conducted from the inception until 5th of February 2024.
Family members' experiences of surrogate decision-making in hospice care: A systematic review of qualitative studies.
Int J Nurs Stud
December 2024
Department of Nursing, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University, Chengdu, China. Electronic address:
Background: Surrogate decision-makers play a key role in determining whether end-of-life patients receive hospice care. There is a need to better understand families' experiences of surrogate decision-making in hospice care for end-of-life patients to provide a basis for developing targeted interventions, such as decision support tools or counseling, to help family members navigate the decision-making process.
Aim: The aim was to analyze and synthesize global qualitative data on family members' experiences of surrogate decision-making regarding whether to receive hospice care for end-of-life patients.
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