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Evaluation of cord management strategies in intrauterine growth-restricted infants: a systematic review and meta-analysis.
Eur J Pediatr
January 2025
Medical Research Group of Egypt, Negida Academy, Arlington, MA, USA.
Delayed cord clamping (DCC) has been widely adopted in both term and preterm infants to improve neonatal outcomes by increasing blood volume and supporting oxygenation. However, the optimal cord management for intrauterine growth-restricted (IUGR) infants is unclear. To systematically review and meta-analyze the effects of DCC compared to early cord clamping (ECC) in IUGR infants.
View Article and Find Full Text PDFIncreased Risk of Persistent Pulmonary Hypertension of the Newborn in Twin Anaemia Polycythaemia Sequence Donors.
Fetal Diagn Ther
November 2024
Division of Fetal Therapy, Department of Obstetrics, Leiden University Medical Center, Leiden, The Netherlands.
Article Synopsis
- * Among 100 TAPS pregnancies, 32% experienced respiratory distress syndrome (RDS), 13% had bronchopulmonary dysplasia (BPD), and 7% had persistent pulmonary hypertension of the newborn (PPHN), with donors showing a higher incidence of PPHN.
- * The findings indicated that lower gestational age and severe fetal anaemia are significant risk factors for PPHN in TAPS twins, highlighting the need for specialized medical care during birth to manage potential complications.
Elevated Interleukin-6 Levels as a Potential Marker of Neonatal Morbidity in Full-term Infants With Polycythemia: A Prospective Study.
J Pediatr Hematol Oncol
January 2025
Faculty of Medicine, Maltepe University, Istanbul, Turkey.
Article Synopsis
- The study aimed to investigate the levels of interleukin-6 (IL-6) and C-reactive protein (CRP) as infection markers in newborns with polycythemia in a neonatal intensive care unit setting.
- Infants over 37 weeks gestational age were included, and those with certain medical conditions were excluded; blood samples were taken to measure these markers and categorize infants into 'polycythemia' or 'control' groups based on their hematocrit levels.
- Results showed significantly higher IL-6 levels in the polycythemia group compared to controls, indicating possible increased inflammation, while CRP levels were elevated but not statistically significant between the groups. *
Predictive Indicators and Outcomes of Pregnancies Affected by Stage I Twin-Twin Transfusion Syndrome Treated With Fetoscopic Laser Photocoagulation.
Prenat Diagn
November 2024
Maternal Fetal Medicine, Osaka Women's and Children's Hospital, Izumi, Japan.
Article Synopsis
- * Out of 272 twin pairs, the survival rates were very high, with 98% of at least one twin surviving and 85% for both, while 93% of recipient twins and 90% of donor twins survived.
- * The research identifies preoperative anemia-polycythemia sequence and arterio-arterial vascular anastomosis (AAA) as significant risk factors for mortality in donor twins after FLP, although the exact mechanisms of AAA need further investigation.
A Study on the Effect of Umbilical Cord Milking Along With Delayed Cord Clamping on Hematological Parameters in Comparison to Delayed Cord Clamping Alone in Moderate-to-Late Preterm Newborns.
Cureus
September 2024
Child Health Nursing, Srimati Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Background Anemia, particularly iron deficiency anemia (IDA), is a global public health issue with serious implications for infant cognitive and developmental outcomes. Preterm infants are especially vulnerable to IDA due to reduced placental blood transfer at birth. Delayed cord clamping (DCC) and umbilical cord milking (UCM) are interventions aimed at enhancing this blood transfer, thereby improving neonatal iron status.
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