Two saponins, designated as bacopaside I and II, have been isolated from Bacopa monniera Wettst. and their structures have been elucidated as 3-O-alpha-L-arabinofuranosyl-(1-->2)-[6-O-sulphonyl-beta-D-glucopyranosyl-(1-->3)]-alpha-L-arabinopyranosyl pseudojujubogenin (1) and 3-O-alpha-L-arabinofuranosyl-(1-->2)-[beta-D-glucopyranosyl (1-->3)]-beta-D-glucopyranosyl pseudojujubogenin (2) mainly on the basis of 2D NMR and other spectral analyses.
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http://dx.doi.org/10.1016/s0031-9422(01)00275-8 | DOI Listing |
Int Immunopharmacol
October 2024
Department of Biochemistry, University of Kerala, Kariavattom Campus, Thiruvanthapuram, Kerala 695 581, India. Electronic address:
Biotechnol Appl Biochem
August 2024
Department of Basic Medical Sciences, College of Medicine, Prince Sattam Bin Abdulaziz University, Al-Kharj, Kingdom of Saudi Arabia.
Obesity is one of the more complicated diseases, it can induce numerous life-threatening diseases mainly diabetes mellitus, cardiovascular disease, hypertension, and certain cancers. In this study, we assessed the efficacy of bacoside-A (a dammarane-type triterpenoid saponin derived from the plant Bacopa monniera Linn.) on the adipogenesis of 3T3-L1 preadipocytes.
View Article and Find Full Text PDFBiol Pharm Bull
February 2023
Division of Integrated Pharmaceutical Sciences, Kyoto Pharmaceutical University.
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by dementia. The most characteristic pathological changes in AD brain include extracellular amyloid-β (Aβ) accumulation and neuronal loss. Particularly, cholinergic neurons in the nucleus basalis of Meynert are some of the first neuronal groups to degenerate; accumulating evidence suggests that Aβ oligomers are the primary form of neurotoxicity.
View Article and Find Full Text PDFNutrients
November 2022
Centre for Human Psychopharmacology, Swinburne University, Melbourne, VIC 3122, Australia.
Previous randomized controlled trials examining cognitive and mood effects of combination multivitamin supplements in healthy, non-clinical adults have reported mixed results. One purported explanation for this is that the dietary status of participants at the start of supplement interventions may influence the magnitude of the effect of supplementation. In this study, we evaluated the effect of a multinutrient formula containing B group vitamins, and on memory, attention, mood and biochemical markers of nutrient status in middle-aged adults ( 52.
View Article and Find Full Text PDFMuscle Nerve
February 2023
Neuromuscular Department, Stanford University, Stanford, California.
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