[Rheological of blood and oxygen transport in long-term adaptation to muscular load].

Ross Fiziol Zh Im I M Sechenova

Pedagogical University, 150000, Yaroslavl, 108 Respublikanskaya St., Russia.

Published: July 2001

The blood viscosity became reduced after a long-term muscular adaptation in dogs. The main adaptation mechanism is associated with an autoregulated haemodilution and improvement of the red blood cells' microrheology (deformities and aggregation). The findings suggest that reduction in the haemodilution and the blood oxygen capacity are accompanied by a heightened efficiency of the oxygen transport. A sufficient correlation exists between the blood fluidity parameters and the oxygen balance in the body. Value of the optimum haematocrit in oxygen transport, is discussed.

Download full-text PDF

Source

Publication Analysis

Top Keywords

oxygen transport
12
blood oxygen
8
oxygen
5
[rheological blood
4
transport long-term
4
long-term adaptation
4
adaptation muscular
4
muscular load]
4
blood
4
load] blood
4

Similar Publications

Chalcogen Substitution-Modulated Molecule-Electrode Coupling in Single-Molecule Junctions.

Langmuir

January 2025

Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, 928 Second Street, Zhejiang, Hangzhou 310018, China.

Molecule-electrode interfaces play a pivotal role in defining the electron transport properties of molecular electronic devices. While extensive research has concentrated on optimizing molecule-electrode coupling (MEC) involving electrode materials and molecular anchoring groups, the role of the molecular backbone structure in modulating MEC is equally vital. Additionally, it is known that the incorporation of heteroatoms into the molecular backbone notably influences factors such as energy levels and conductive characteristics.

View Article and Find Full Text PDF

Oxygen controls most metazoan metabolism, yet in mammals, tissue O levels vary widely. While extensive research has explored cellular responses to hypoxia, understanding how cells respond to physiologically high O levels remains uncertain. To address this problem, we investigated respiratory epithelia as their contact with air exposes them to some of the highest O levels in the body.

View Article and Find Full Text PDF

Aim: To study the effect and elucidate the underlying mechanisms of VDAC1-ΔC on autophagy in renal tubular epithelial cells injured by hypoxia/reoxygenation.

Methods: C57/BL6 mice were randomly divided into groups: sham operation group, IRI 1d group and IRI 2d group. The inner canthal blood of mice was collected to detect the levels of serum creatinine and urea nitrogen and kidney tissues were sampled, and sections were stained with Periodic acid-Schiff for morphological evaluation.

View Article and Find Full Text PDF

Bacopa monnieri Extract Diminish Hypoxia-Induced Anxiety by Regulating HIF-1α Signaling and Enhancing the Antioxidant Defense System in Hippocampus.

Neuromolecular Med

January 2025

Biochemistry and Molecular Biology Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221 005, India.

Hypoxia is a significant stressor, and stabilized hypoxia-inducible factor-1α (HIF-1α) regulates the expression of numerous genes, leading to various biochemical, molecular, physiological and genomic changes. The body's oxygen-sensing system activates gene expression to protect brain tissues from hypoxia. Gamma-aminobutyric acid, an inhibitory neurotransmitter, regulates brain excitability during hypoxia through the activation of HIF-1 α.

View Article and Find Full Text PDF

Non-invasive ventilation has been used as a pre-oxygenation strategy for rapid sequence intubation in the emergency department and the intensive care unit, yet, limited research has examined its use in the transport setting. These case reports discuss the use of non-invasive ventilation via a Hamilton T1 ventilator (Hamilton Medical) during transport by an air medical crew for pre-oxygenation before intubation in two cases. In both cases, a non-invasive, bilevel-positive airway pressure mode with a backup rate was used to achieve adequate airway pressures while allowing for a two-handed seal by one EMS clinician as the other prepared the equipment and medications.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!