Purpose: To evaluate the influence on postoperative inflammation of lens epithelial cell (LEC) removal after phacoemulsification.
Setting: Department of Ophthalmology, University of Vienna, Vienna, Austria.
Methods: This randomized prospective single-surgeon study comprised 60 patients with senile cataract only. After a temporal clear corneal incision was made and phacoemulsification performed, no LECs were removed in Group A, LECs in the nasal half were removed in Group B, and LECs were removed from the entire anterior capsule in Group C. The LECs were removed with a Rentsch capsule curette (Geuder). In all eyes, a foldable hydrogel intraocular lens (Hydroview, Bausch & Lomb) was implanted. Anterior chamber flare was evaluated through dilated pupils in a double-masked fashion using a Kowa FC-1000 laser flare-cell meter (LFCM). Measurements were done preoperatively as well as 1, 3, 7, 14, and 28 days and 3, 6, 12, and 24 months postoperatively.
Results: In all 3 groups, the flare and cell values increased on the first postoperative day followed by a successive decrease thereafter. One month after surgery, the blood-aqueous barrier (BAB) was nearly restored in all groups. Between the first and fourth week, the flare values in Groups B and C were slightly lower than in Group A; however, mean flare and cell values among groups were not statistically significantly different at any measurement.
Conclusion: The removal of LECs from the anterior capsule with a Rentsch curette did not influence postoperative BAB changes detected using an LFCM.
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http://dx.doi.org/10.1016/s0886-3350(01)00795-7 | DOI Listing |
BMC Ophthalmol
January 2025
Eye Institute, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China.
Background: Human anterior lens capsules (ALCs) have great potential in the treatment of multiple eye diseases, including corneal ulcers, glaucoma, age-related macular degeneration and macular holes. ALCs are also regarded as promising scaffolds for various ocular cells. Here, we investigated different decellularization methods for removing lens epithelial cells (LECs) that adhered to ALCs.
View Article and Find Full Text PDFGut Liver
January 2025
Department of Gastroenterology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Peroral flexible endoscopy is a minimally invasive technique that enables the local resection of gastric subepithelial tumors (SETs) with malignant potential. Resection techniques are mainly chosen on the basis of the lesion size. Minute SETs less than 1 cm should be managed through a watch and wait strategy, with the exception of histologically diagnosed superficial lesions, which require endoscopic mucosal resection or endoscopic submucosal dissection.
View Article and Find Full Text PDFPilot Feasibility Stud
January 2025
Department of Clinical Science, Intervention and Technology (CLINTEC), Division of Surgery and Oncology, Karolinska Institutet, Hälsovägen 13, 141 57, Huddinge, Stockholm, Sweden.
Background: The standard treatment for advanced gastric cancer without metastasis is gastrectomy in combination with chemotherapy. Some patients cannot tolerate such treatment because of old age or comorbidities. In this study, we want to test the feasibility of Laparoscopic and Endoscopic Cooperative Surgery (LECS) as a less invasive treatment option.
View Article and Find Full Text PDFPLoS Biol
October 2024
Laboratory of Cell Biology, Department of Biological Sciences, Graduate School of Science, Osaka University, Osaka, Japan.
Molecules
July 2024
Instituto Politécnico Nacional, Escuela Nacional de Ciencias Biológicas, Departamento de Ingeniería Bioquímica, Avenida Wilfrido Massieu s/n, Unidad Profesional Adolfo López Mateos, Alcaldía Gustavo A. Madero, Mexico City 07738, Mexico.
Excessive water hyacinth growth in aquatic environments and metanil yellow (MY) dye in industrial wastewater pose severe environmental and public health challenges. Therefore, this study evaluated the effects of various process factors on batch MY biosorption onto water hyacinth leaves (LECs) and MY biosorption kinetics, equilibrium, and thermodynamics. The optimal pH for MY biosorption by LECs was 1.
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