An analysis was performed of 112 protocols of autopsies of those adult subjects having died of generalized tuberculosis presenting with tuberculous meningitis over the last 50 years. A significant pathomorphism of tuberculosis of meninges and central nervous system was found out to have taken place over that period of time. Over the last decade, reversion of generalized tuberculosis has been noted together with an increase in the incidence of tuberculous meningitis and younger age of those patients who die of grave forms of the specific process.

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