The aim of this study was to cross-validate the Benzodiazepine Dependence Self-Report Questionnaire (Bendep-SRQ), which reflects the severity of benzodiazepine (BZD) dependence. The Bendep-SRQ, Symptom Checklist-90 (SCL-90) Schedules for Clinical Assessments in Neuropsychiatry (SCAN), and Addiction Severity Index-Revised (ASI-R) were administered to 102 general practice (GP) patients and 126 psychiatric outpatients who were using BZDs. The scalability and reliability of the Bendep-SRQ scales were reassessed in terms of Rasch homogeneity, subject discriminability, item discriminability, and test-retest stability. Present and original Rasch item orders were compared to evaluate construct validity. A matrix of all measures was factor-analyzed to assess concurrent and discriminant validity. The scalability of the Bendep-SRQ scales was confirmed. The reliability results were fairly good. Present and original Rasch item orders corresponded. The Bendep-SRQ scales and concurrent measures had high loadings on one factor, the discriminant measures on two other factors. In spite of some differences with respect to sociodemographic characteristics and pattern of BZD use, the cross-validation results agreed well with the results of the original study on the Bendep-SRQ. The Bendep-SRQ has presently acquired enough support of favorable and consistent results for clinical and scientific use.
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http://dx.doi.org/10.1053/comp.2001.26275 | DOI Listing |
BMC Psychiatry
April 2021
Medical Headquarters, Eisai Co., Ltd., Nishigoken-cho 13-1, Shinjuku-ku, Tokyo, 162-0812, Japan.
Background: Although long-term use of benzodiazepines and benzodiazepine receptor agonists (BZDs) has been associated with an increased risk of dependence, the incidence, details of clinical manifestations, and triggering factors of withdrawal symptoms associated with long-term BZD use at common clinical doses remain unclear.
Methods: In a multicenter, open-label study of 123 Japanese patients with insomnia, patients were given a common clinical dose of eszopiclone (2 mg) for 24 weeks, and then treatment was abruptly discontinued. Withdrawal symptoms were evaluated using the Benzodiazepine Hypnotics Withdrawal Symptom Scale (BHWSS).
Trends Psychiatry Psychother
September 2021
Núcleo de Pesquisa em Saúde e Uso de Substâncias (NEPSIS), Departamento de Psicobiologia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Objective: To assess psychometric properties of the Benzodiazepine Dependence Self-Report Questionnaire - Portuguese Version (BENDEP-SRQ-PV) in a sample of Brazilian chronic hypnotic users.
Methods: One hundred and seventy-nine chronic hypnotic users (benzodiazepines and Z-drugs) were recruited, attended a psychiatric evaluation, and answered the BENDEP-SRQ-PV. Factor structure, reliability, and influence of covariates (dependence diagnosis and type of drug consumed) were assessed in a structural equation modelling environment.
Compr Psychiatry
June 2004
Department of Psychiatry, University Medical Centre St. Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
The aim of this study was to identify risk factors for benzodiazepine (BZD) dependence, such as sociodemographic variables, characteristics of BZD use, and psychiatric parameters, which to date have been found to relate inconsistently to indicators of BZD dependence such as chronic BZD use and BZD withdrawal symptoms. The Benzodiazepine Dependence Self-Report Questionnaire (Bendep-SRQ), Schedules for Clinical Assessment in Neuropsychiatry (SCAN), and Symptom Checklist-90 (SCL-90) were administered to 599 outpatients using BZDs. Regression analyses were conducted using BZD dependence diagnoses and severity scales as dependent variables.
View Article and Find Full Text PDFCompr Psychiatry
October 2003
Department of Psychiatry, University Medical Centre St. Radboud, Nijmegen, The Netherlands.
The Benzodiazepine Dependence Self-Report Questionnaire (Bendep-SRQ) measures the severity of benzodiazepine (BZ) dependence on four domains: awareness of problematic use, preoccupation with the availability of BZ, lack of compliance with the therapeutic regimen, and withdrawal. Although promising results of the Bendep-SRQ have been obtained in cross-sectional studies, no attention has been paid to its clinical relevance during BZ withdrawal, i.e.
View Article and Find Full Text PDFProg Neuropsychopharmacol Biol Psychiatry
June 2002
Department of Psychiatry, University Medical Center St. Radboud Nijmegen, PO Box 9101, Internal Postnumber 332, 6500 HB, Nijmegen, The Netherlands.
The aim of the present study was to compare the possible dependence potential of antidepressants (ADs) to benzodiazepines (BZDs). The Schedules for Clinical Assessment in Neuropsychiatry (SCAN), the Benzodiazepine Dependence Self-Report Questionnaire (Bendep-SRQ) and the Symptom Checklist-90 (SCL-90) were administered to 70 psychiatric outpatient BZD users and 54 psychiatric outpatient AD users. Significantly more Diagnostic and Statistical Manual of Mental Disorders, Third Edition Revised (DSM-III-R) as well as International Classification of Diseases, Tenth Edition (ICD-10) past year (PY) and lifetime (LT) dependence diagnoses were made in the BZD group than in the AD group.
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