More than 2000 gray rat specimens and 5 burrows have been examined in several regions of steppe and forest-steppe zones of Ukraine. 24,647 representatives of Arthropoda of 39 taxonomic groups have been collected. Species composition of parasitic mites (Gamasida, Trombiculidae, Myobiidae, Listophoridae) and insects (Anoplura, Siphonaptera) has been defined.
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Opioidergic activation of the descending pain inhibitory system underlies placebo analgesia.
Sci Adv
January 2025
Laboratory for Biofunction Dynamics Imaging, RIKEN Center for Biosystems Dynamics Research, 6-7-3 Minatojima-Minamimachi, Chuo-ku, Kobe, Hyogo 650-0047, Japan.
Placebo analgesia is caused by inactive treatment, implicating endogenous brain function involvement. However, the neurobiological basis remains unclear. In this study, we found that μ-opioid signals in the medial prefrontal cortex (mPFC) activate the descending pain inhibitory system to initiate placebo analgesia in neuropathic pain rats.
View Article and Find Full Text PDFAssessment of complementary white matter microstructural changes and grey matter atrophy in the 6-OHDA-induced model of Parkinson's disease.
Neuroscience
January 2025
Barrow Neuroimaging Innovation Center, Barrow Neurological Institute, Phoenix, AZ, 85013, USA. Electronic address:
Parkinson's disease (PD) is a progressive neurodegenerative disorder that is characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Magnetic resonance imaging (MRI) offers a non-invasive means to study PD and its progression. This study utilized the unilateral 6-hydroxydopamine (6-OHDA) rat model of parkinsonism to assess whether white matter microstructural integrity measured using advanced free-water diffusion tensor imaging metrics (fw-DTI) and gray matter density using voxel-based morphometry (VBM) can serve as imaging biomarkers of pathological changes following nigrostriatal denervation.
View Article and Find Full Text PDFA Systematic Review of Zoonotic Enteric Parasites in Synanthropic Mammalian Species in Florida.
Pathogens
December 2024
Department of Public Health, University of North Florida, Jacksonville, FL 32224, USA.
Florida is home to a vast number of wildlife species that come into close contact with residents and domestic animals. As mammals are competent hosts for many zoonotic diseases, it is important to understand what exposure risks are present for both people and animals. Using Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines, this review analyzed published literature spanning 1963 through 2023 documenting zoonotic enteric parasites in synanthropic wild mammals of Florida, excluding mice and rats.
View Article and Find Full Text PDFAcupuncture at Weizhong (BL40) attenuates acetic acid-induced overactive bladder in rats by regulating brain neural activity through the modulation of mast cells and tibial nerves.
J Integr Med
December 2024
Department of Acupuncture and Moxibustion, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China. Electronic address:
Objective: The present study evaluated the effects of deep acupuncture at Weizhong acupoint (BL40) on bladder function and brain activity in a rat model of overactive bladder (OAB), and investigated the possible mechanisms around the acupuncture area that initiate the effects of acupuncture.
Methods: Adult female Sprague-Dawley rats were randomly divided into six groups, comprising a control group, model group, group treated with deep acupuncture at BL40, group treated with shallow acupuncture at BL40, group treated with acupuncture at non-acupoint next to BL40, and group treated with acupuncture at Xuanzhong (GB39). Urodynamic evaluation was used to observe the urination, and functional magnetic resonance imaging was used to observe the brain activation.
Effects of Aluminum Oxide Nanoparticles in the Spinal Cord of Male Wistar Rats and the Potential Ameliorative Role of Melatonin.
Environ Toxicol
December 2024
Cytology and Histology Department, Veterinary Medicine, Cairo University, Giza, Egypt.
Aluminum oxide nanoparticles (AlO NPs) are widely utilized in vaccine manufacturing and other medical preparations. Melatonin has numerous effects as an antioxidant and anti-apoptotic. The purpose of this study was to examine the beneficial impact of melatonin on AlO NPs toxicity in the spinal cord.
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