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Supratentorial Intracerebral Hematoma as a Rare Complication of Posterior Fossa Surgery in Prone Position: A Case Report with Review of Literature.
Asian J Neurosurg
June 2023
Department of Neurosurgery, SGPGI, Lucknow, Uttar Pradesh, India.
Supratentorial intracerebral hematoma is a rare complication after posterior fossa tumor surgery in prone positioning. Although rare, its occurrence may cause significant impact on survival of the patient. We had described this rare complication and their possible pathophysiology in this report.
View Article and Find Full Text PDFCorrelation between clinical and brain computed tomography findings of stroke patients: A cross-sectional study.
Health Sci Rep
May 2023
Department of Radiology and Radiotherapy, College of Health Sciences Makerere University Kampala Uganda.
Background And Aims: In developing countries, the burden of stroke is growing and causing significant morbidity and disability with high mortality rates. Neuroimaging plays a crucial role in differentiating ischemic stroke from an intracerebral hemorrhage, as well as entities other than stroke. This study sought to determine the correlation between the clinical and brain CT scan findings of stroke patients attending three hospitals in Kampala, Uganda.
View Article and Find Full Text PDFSpectrum of intracranial and spinal epidermoids including unusual locations and imaging findings: A pictorial review.
J Med Imaging Radiat Oncol
February 2023
Neurosurgery, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Pondicherry, India.
Intracranial and spinal epidermoids are benign slow-growing congenital lesions. They are predominantly intradural, extra-axial in location, with intra-axial locations (intra-parenchymal and spinal intramedullary) being rare. The most common locations of intradural epidermoids are cerebellopontine angle cistern followed by supra- and para-sellar regions, and fourth ventricle.
View Article and Find Full Text PDFVisualizing surface marker expression and intratumoral heterogeneity with SERRS-NPs imaging.
Nanotheranostics
March 2022
Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Article Synopsis
- Tumor surface marker expression influences treatment choices, outcomes, and patient survival, but traditional biopsies are invasive and often miss important variations within tumors.
- Researchers studied antibody-conjugated SERRS-NPs to visualize and measure surface markers like EGFR and HER2 in tumors, comparing their effectiveness in both intracranial and peripheral tumor models.
- The SERRS-NP imaging technique provided distinct Raman signals that accurately distinguished levels of surface marker expression, suggesting it could be a non-invasive alternative to biopsies and improve molecular imaging accuracy in clinical settings.
Nanoparticle encapsulated core-shell hydrogel for on-site BMSCs delivery protects from iron overload and enhances functional recovery.
J Control Release
April 2020
Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400030, China; Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02142, USA. Electronic address:
The local microenvironment may influence the success of stem cell therapy. Iron overload occurs in many hemorrhagic injuries due to hemolysis and hemoglobin degradation, which not only mediates local cell injury, but also induces damage to the transplanted cells. Here, an injectable nanoparticle encapsulated core-shell hydrogel was fabricated for simultaneous iron overload clearance and bone marrow mesenchymal stem cells (BMSCs) transplantation following intracerebral hemorrhage (ICH).
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