Optimizing radiation treatment for cervical cancer.

The technical and radiobiological improvements in the science of radiotherapy, coupled with the use of cisplatin-containing regimens concurrent with radiation therapy, have improved dramatically the cure rate and quality of Life for cervical cancer survivors. Further research is necessary to understand the complex dose distribution of external beam and intracavitary radiation and their relationship to tumor control and complications. With the use of CT-compatible applicators for intracavitary radiation, CT simulation and three-dimensional treatment planning for EBRT, the radiation oncology community should meet this challenge.